Gülaştı Ferdi, Gülaştı Sevil, Can Büşra Ceyhan, Öztürk Hakan, Sarı Sinem
Department of Anesthesiology and Reanimation, Faculty of Medicine, Adnan Menderes University, Aydın 09010, Türkiye.
Department of Cardiology, Faculty of Medicine, Adnan Menderes University, Aydın 09010, Türkiye.
Diagnostics (Basel). 2025 May 31;15(11):1404. doi: 10.3390/diagnostics15111404.
Hypotension is a common adverse event after the induction of general anesthesia and may lead to serious complications. The Tricuspid Annular Plane Systolic Excursion (TAPSE)/Pulmonary Arterial Systolic Pressure (PASP) ratio is an echocardiographic parameter reflecting right ventricular (RV) function and pulmonary circulation. This study aimed to evaluate the predictive value of the TAPSE/PASP ratio for hypotension after general anesthesia induction. This prospective observational study included 79 patients with no known cardiac disease who were scheduled for elective surgery and classified as having a physical status of I-III according to the American Society of Anesthesiologists (ASA). TAPSE, PASP, and RV function were assessed using transthoracic echocardiography (TTE) within 5-30 min before surgery, and their hemodynamic changes after general anesthesia induction were recorded. Data analysis revealed a significant association between the TAPSE/PASP ratio and the occurrence of hypotension following the induction of general anesthesia ( < 0.001). In addition, a cut-off value of ≤1.98 was determined for predicting hypotension, which demonstrated a sensitivity of 72.5% and a specificity of 64.1% (AUC = 0.733, 95% CI: 0.621-0.826, < 0.001). The TAPSE/PASP ratio is a potential predictor of hypotension following the induction of general anesthesia. Further studies are required to validate its predictive accuracy and clinical utility in perioperative hemodynamic management.
低血压是全身麻醉诱导后常见的不良事件，可能导致严重并发症。三尖瓣环平面收缩期位移（TAPSE）/肺动脉收缩压（PASP）比值是反映右心室（RV）功能和肺循环的超声心动图参数。本研究旨在评估TAPSE/PASP比值对全身麻醉诱导后低血压的预测价值。这项前瞻性观察性研究纳入了79例无已知心脏病且计划接受择期手术的患者，根据美国麻醉医师协会（ASA）将其身体状况分类为I-III级。在手术前5-30分钟内使用经胸超声心动图（TTE）评估TAPSE、PASP和RV功能，并记录全身麻醉诱导后的血流动力学变化。数据分析显示，TAPSE/PASP比值与全身麻醉诱导后低血压的发生之间存在显著关联（<0.001）。此外，确定预测低血压的截断值≤1.98，其敏感性为72.5%，特异性为64.1%（AUC = 0.733，95%CI：0.621-0.826，<0.001）。TAPSE/PASP比值是全身麻醉诱导后低血压的潜在预测指标。需要进一步研究以验证其在围手术期血流动力学管理中的预测准确性和临床实用性。
