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减孔全机器人胰十二指肠切除术与传统全机器人及腹腔镜胰十二指肠切除术的比较

Comparison of Reduced-Port Totally Robotic Pancreaticoduodenectomy with Conventional Totally Robotic and Laparoscopic Pancreaticoduodenectomy.

作者信息

Lee Boram, Han Ho-Seong, Yoon Yoo-Seok, Lee Jun Suh

机构信息

Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si 13605, Gyeonggi-do, Republic of Korea.

出版信息

J Clin Med. 2025 Jun 4;14(11):3960. doi: 10.3390/jcm14113960.

DOI:10.3390/jcm14113960
PMID:40507722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12155746/
Abstract

Reduced-port totally robotic pancreaticoduodenectomy (rpRPD) has been introduced to address limitations of conventional robotic pancreaticoduodenectomy (cRPD), particularly regarding assistant mobility and visualization. This study aimed to evaluate the clinical feasibility and procedural consistency of rpRPD in comparison with cRPD and laparoscopic pancreaticoduodenectomy (LPD). : We conducted a retrospective cohort study of patients who underwent pancreaticoduodenectomy between January 2015 and December 2024. Patients were categorized into rpRPD (n = 40), cRPD (n = 60), and LPD (n = 262) groups. Clinical outcomes and learning curves were compared using regression and cumulative sum (CUSUM) analysis. : Baseline characteristics were similar across groups. The rpRPD group demonstrated significantly shorter operative time ( < 0.001) and lower blood loss ( < 0.05) than cRPD, with no significant differences in postoperative complications or hospital stay. The learning curve analysis revealed that rpRPD had lower variance (5839.3 vs. 8919.1) and more stable performance than cRPD despite a slightly longer stabilization point. Lymph node retrieval was comparable across groups, supporting oncological equivalence. : rpRPD offers comparable perioperative and oncologic outcomes to cRPD and LPD while improving operative efficiency and procedural predictability. It represents a technically feasible and safe option for minimally invasive pancreatic surgery.

摘要

为解决传统机器人胰十二指肠切除术(cRPD)的局限性,尤其是在助手移动性和可视化方面的局限,减少端口全机器人胰十二指肠切除术(rpRPD)应运而生。本研究旨在评估rpRPD与cRPD及腹腔镜胰十二指肠切除术(LPD)相比的临床可行性和手术操作的一致性。我们对2015年1月至2024年12月期间接受胰十二指肠切除术的患者进行了一项回顾性队列研究。患者被分为rpRPD组(n = 40)、cRPD组(n = 60)和LPD组(n = 262)。使用回归分析和累积和(CUSUM)分析比较临床结果和学习曲线。各组的基线特征相似。rpRPD组的手术时间明显短于cRPD组(<0.001),失血量也低于cRPD组(<0.05),术后并发症或住院时间无显著差异。学习曲线分析显示,尽管rpRPD的稳定点稍长,但与cRPD相比,其方差更低(5839.3对8919.1),性能更稳定。各组的淋巴结清扫情况相当,支持肿瘤学等效性。rpRPD在围手术期和肿瘤学结果方面与cRPD和LPD相当,同时提高了手术效率和手术操作的可预测性。它是微创胰腺手术中一种技术上可行且安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/4e558c82a743/jcm-14-03960-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/39008c3b1889/jcm-14-03960-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/16e043a6605c/jcm-14-03960-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/4e558c82a743/jcm-14-03960-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/39008c3b1889/jcm-14-03960-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/16e043a6605c/jcm-14-03960-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c127/12155746/4e558c82a743/jcm-14-03960-g003.jpg

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本文引用的文献

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Short-term surgical outcomes of open, laparoscopic, and robot-assisted pancreatoduodenectomy: A comparative, single-center, retrospective study.开腹、腹腔镜和机器人辅助胰十二指肠切除术的短期手术结果:一项比较、单中心、回顾性研究。
Asian J Endosc Surg. 2025 Jan-Dec;18(1):e13397. doi: 10.1111/ases.13397.
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Comparison of Laparoscopic and Open Pancreaticoduodenectomy on Operative Time, Oncological Outcomes, Bleeding, Morbidity, and Mortality.腹腔镜与开放胰十二指肠切除术在手术时间、肿瘤学结局、出血、并发症及死亡率方面的比较
Cureus. 2024 Feb 1;16(2):e53387. doi: 10.7759/cureus.53387. eCollection 2024 Feb.
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Minimally invasive pancreaticoduodenectomy: A favorable approach for frail patients with pancreatic cancer.
微创胰十二指肠切除术:胰腺癌体弱患者的理想术式。
Surgery. 2024 Apr;175(4):1168-1175. doi: 10.1016/j.surg.2023.12.022. Epub 2024 Feb 2.
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A Growing Armamentarium for the Robotic Pancreas Surgeon?用于机器人胰腺手术的器械库在不断扩充?
Ann Surg Open. 2023 May 5;4(2):e282. doi: 10.1097/AS9.0000000000000282. eCollection 2023 Jun.
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Comparison of surgical outcomes among open, laparoscopic, and robotic pancreatoduodenectomy: a single-center retrospective study.开腹、腹腔镜和机器人胰十二指肠切除术的手术结果比较:单中心回顾性研究。
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Which one is better? Laparoscopic versus robotic reconstruction in the remnant soft pancreas with a small pancreatic duct following pancreaticoduodenectomy: a multicenter study with propensity score matching analysis.胰十二指肠切除术后残胰软胰腺小胰管中腹腔镜与机器人重建的比较:一项采用倾向评分匹配分析的多中心研究。
Surg Endosc. 2023 May;37(5):4028-4039. doi: 10.1007/s00464-022-09602-2. Epub 2022 Sep 12.
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