Suppr超能文献

由……引起的腹腔内感染患者的临床特征 。 你提供的原文似乎不完整,“by”后面缺少具体内容。

Clinical Characteristics of Patients with Intra-Abdominal Infection Caused by .

作者信息

Chen Chien-Liang, Tsai Chun-Chou, Chen Wei-Ping, Chang Feng-Yee, Yu Ching-Mei, Shang Hung-Sheng, Siu Leung-Kei, Yang Ya-Sung, Lin Jung-Chung, Wang Ching-Hsun

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Zuoying Armed Forces General Hospital, Kaohsiung 81300, Taiwan.

Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.

出版信息

J Clin Med. 2025 Jun 4;14(11):3974. doi: 10.3390/jcm14113974.

Abstract

Intra-abdominal infections (IAIs) caused by have rarely been reported. This study aimed to describe the clinical characteristics and risk factors for mortality among patients with IAIs. A retrospective study was conducted on inpatients with IAIs caused by at Tri Service General Hospital from 2004 to 2017. Clinical and microbiologic data of the included cases were reviewed via medical charts and microbiology databases. Multivariable logistic regression analyses were performed to identify risk factors for in-hospital death. In total, 110 patients were diagnosed with IAIs. Malignancy (56.3%) and liver cirrhosis (35.3%) were the most commonly identified underlying diseases. The major causes of IAIs were biliary tract infection (42.7%), recent abdominal surgery (35.4%), and spontaneous bacterial peritonitis (20.0%). Polymicrobial infections were observed in 84 (76.4%) patients. In addition to , co-cultured bacteria ( = 140) included , representing 19.3% (27/140) of the total isolates, and non-fermentative aerobes, comprising 29.3% (41/140). In addition, anaerobic bacteria and fungi accounted for 9.2% (13/140) and 10% (14/140), respectively. The overall mortality rate was 40.9%. Multivariable logistic regression analysis revealed that high Sequential Organ Failure Assessment scores and malignancies were independent risk factors for mortality, while the immediate administration of appropriate antibiotics targeting was a protective factor ( < 0.05). Patients with an underlying malignancy or liver cirrhosis were at risk for IAIs caused by . The prompt initiation of effective antibiotics against is critical for achieving favorable outcomes.

摘要

由[未提及具体病菌名称]引起的腹腔内感染(IAIs)鲜有报道。本研究旨在描述[未提及具体病菌名称]所致IAIs患者的临床特征及死亡风险因素。对2004年至2017年三军总医院收治的由[未提及具体病菌名称]引起IAIs的住院患者进行了一项回顾性研究。通过病历和微生物学数据库对纳入病例的临床和微生物学数据进行了回顾。进行多变量逻辑回归分析以确定院内死亡的风险因素。总共110例患者被诊断为[未提及具体病菌名称]所致IAIs。恶性肿瘤(56.3%)和肝硬化(35.3%)是最常见的基础疾病。[未提及具体病菌名称]所致IAIs的主要原因是胆道感染(42.7%)、近期腹部手术(35.4%)和自发性细菌性腹膜炎(20.0%)。84例(76.4%)患者观察到多微生物感染。除了[未提及具体病菌名称],共培养的细菌(n = 140)包括[未提及具体细菌名称],占分离菌株总数的19.3%(27/140),以及非发酵需氧菌,占29.3%(41/140)。此外,厌氧菌和真菌分别占9.2%(13/140)和10%(14/140)。总体死亡率为40.9%。多变量逻辑回归分析显示,高序贯器官衰竭评估评分和恶性肿瘤是死亡的独立危险因素,而立即给予针对[未提及具体病菌名称]的适当抗生素是一个保护因素(P < 0.05)。有潜在恶性肿瘤或肝硬化的患者有发生[未提及具体病菌名称]所致IAIs的风险。迅速开始针对[未提及具体病菌名称]的有效抗生素治疗对于取得良好预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b55/12155589/4944dc27de3d/jcm-14-03974-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验