Hiller Marco, Kohl Matthias, Chaudry Oliver, Engelke Klaus, von Stengel Simon, Kemmler Wolfgang
Institute of Radiology, University Hospital Erlangen, 91054 Erlangen, Germany.
Department of Health, Medical and Life Sciences, University of Furtwangen, 78056 Schwenningen, Germany.
Healthcare (Basel). 2025 May 27;13(11):1262. doi: 10.3390/healthcare13111262.
: Fatty infiltration of muscle is a predictor of degeneration. The present study determined the effect of an active spinal orthosis on muscle quality as determined by fatty infiltration in paraspinal muscles in older women with vertebral fractures and kyphosis. : Twenty-one community-dwelling women ≥65 years with chronic back pain and vertebral fractures ≥3 months were randomly allocated to a group which wore the Spinomed active orthoses 2 × 2-3 h/d for 16 weeks (SOG: = 11) or an untreated control group (CG: = 10). Outcomes of the present study were parameters related to fatty infiltration of the musculi erector spinae and psoas major as determined by Magnetic Resonance Imaging (MRI). We applied a per protocol analysis; data were consistently adjusted for baseline values applying an ANCOVA. : Despite positive trends for all MRI parameters, no significant effects of the active spinal orthosis on fat infiltration of the musculus erector spinae were observed. Significant positive effects were, however, determined for musculus psoas major intra-fascial volume ( = 0.021; d': 1.18) and muscle tissue volume ( = 0.001; d': 1.80). No further significant effects on m. psoas major intra-fascial or muscle tissue average fat fraction or m. psoas major intramuscular adipose tissue volume were assessed. Of importance, no changes in variables that might have confounded the present result were reported. : In line with recent exercise studies, the present high-volume, low-intensity back-strengthening intervention, induced by an active spinal orthosis, failed to generate significant effects on MRI measures of the m. erector spinae. On the other hand, significant effects on m. psoas major hypertrophy, albeit not fatty muscle infiltration, were determined. This new and unexpected finding should be confirmed by future studies.
肌肉脂肪浸润是退变的一个预测指标。本研究确定了一种主动式脊柱矫形器对患有椎体骨折和脊柱后凸的老年女性椎旁肌脂肪浸润所确定的肌肉质量的影响。：21名年龄≥65岁、患有慢性背痛且椎体骨折≥3个月的社区居住女性被随机分配到一组，该组每天佩戴Spinomed主动式矫形器2×2 - 3小时，持续16周（SOG：n = 11）或未治疗的对照组（CG：n = 10）。本研究的结果是通过磁共振成像（MRI）确定的与竖脊肌和腰大肌脂肪浸润相关的参数。我们采用了符合方案分析；数据通过协方差分析（ANCOVA）持续根据基线值进行调整。：尽管所有MRI参数都有积极趋势，但未观察到主动式脊柱矫形器对竖脊肌脂肪浸润有显著影响。然而，确定腰大肌筋膜内体积有显著积极影响（P = 0.021；d'：1.18）和肌肉组织体积（P = 0.001；d'：1.80）。未评估对腰大肌筋膜内或肌肉组织平均脂肪分数或腰大肌肌内脂肪组织体积的进一步显著影响。重要的是，未报告可能混淆本结果的变量有变化。：与最近的运动研究一致，由主动式脊柱矫形器引起的这种高容量、低强度的背部强化干预未能对竖脊肌的MRI测量产生显著影响。另一方面，确定了对腰大肌肥大有显著影响，尽管不是对肌肉脂肪浸润有影响。这一新的意外发现应通过未来的研究加以证实。
