2023 - 2024年中国盐城儿童腺病毒的流行病学特征
Epidemiological characteristics of adenovirus in children in Yancheng, China, 2023-2024.
作者信息
Chen Guoqing, Cao Jin, Qu Yingli, Tian Wenyan, Shen Peng, Liu Xuan, Luo Qin, Song Qinqin, Wen Qi, Xue Guangyu, Hu Yuting, Shi Qiangqiang, Zhang Lifeng, Zhu Rundong, Song Juan, Han Jun
机构信息
Key Laboratory of Molecular Biology in Public Health, Yancheng Center for Disease Prevention and Control, Yancheng, China.
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
出版信息
Front Cell Infect Microbiol. 2025 May 29;15:1587257. doi: 10.3389/fcimb.2025.1587257. eCollection 2025.
OBJECTIVE
To understand the epidemiology and evolutionary characteristics of human adenovirus (HAdV) infecting children in Yancheng, China, during the winter of 2023-2024.
METHODS
HAdV-positive throat swab samples were collected from pediatric patients in Yancheng. The Hexon, Penton base, and Fiber genes were amplified and sequenced for typing and phylogenetic analysis of HAdV.
RESULTS
170 HAdV-positive samples were collected and identified from children with acute respiratory infection (ARI) in Yancheng. A total of 133 samples were successfully amplified and sequenced for Hexon, Penton base, and Fiber genes. Phylogenetic analysis showed that HAdV-B3 was the dominant circulating strain, and two strains of B21, one strain of C1 and one strain of C5 were also identified.
CONCLUSION
During the winter of 2023-2024, HAdV infecting children in Yancheng was mainly the B3 type.
目的
了解2023 - 2024年冬季中国盐城地区感染儿童的人腺病毒（HAdV）的流行病学及进化特征。
方法
从盐城地区儿科患者中采集HAdV阳性咽拭子样本。对六邻体、五邻体基座和纤维基因进行扩增及测序，用于HAdV的分型和系统发育分析。
结果
从盐城地区急性呼吸道感染（ARI）儿童中收集并鉴定出170份HAdV阳性样本。共133份样本成功扩增并对六邻体、五邻体基座和纤维基因进行了测序。系统发育分析表明，HAdV - B3是主要的流行毒株，还鉴定出2株B21、1株C1和1株C5。
结论
2023 - 2024年冬季，盐城地区感染儿童的HAdV主要为B3型。
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