Singh Akansha, Ambad Ranjit S, Jha Roshan Kumar
Department of Biochemistry Jawaharlal Nehru Medical College, Sawangi (M), Wardha, Maharashtra, India.
Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (M), Wardha, Maharashtra, India.
J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S913-S915. doi: 10.4103/jpbs.jpbs_1975_24. Epub 2025 Feb 21.
T2DM is strongly associated with an increased prevalence of cardiovascular disease (CVD). It has been established that CVD is the main cause of mortality among patients with type 2 diabetes mellitus (T2DM) contributing to 80% of fatal outcomes. The consistent relationship between T2DM and CVD is well-established in observational studies, meta-analyses, and has an easily discernible biological mechanism.
This was a cross-sectional study consisting of 100 subjects of diabetic and non-diabetic with CHD attending medicine outpatient department (OPD).
The study highlights that diabetes significantly exacerbates the metabolic and cardiovascular risks in coronary heart disease (CHD) patients, affecting lipid profiles, glycemic control, and long-term survival. Effective management of these parameters is crucial to improving outcomes in diabetic CHD patients. Postoperative morbidity and early mortality were not substantially affected by diabetes; however, long-term survival in diabetic CHD patients was markedly diminished, highlighting the enduring effects of diabetes on cardiovascular health.
2型糖尿病(T2DM)与心血管疾病(CVD)患病率增加密切相关。已确定心血管疾病是2型糖尿病(T2DM)患者死亡的主要原因,占致命结局的80%。T2DM与CVD之间的一致性关系在观察性研究、荟萃分析中已得到充分证实,并且有易于识别的生物学机制。
这是一项横断面研究,包括100名患有冠心病的糖尿病和非糖尿病患者,他们在医学门诊就诊。
该研究强调,糖尿病会显著加剧冠心病(CHD)患者的代谢和心血管风险,影响血脂水平、血糖控制和长期生存。有效管理这些参数对于改善糖尿病冠心病患者的预后至关重要。糖尿病对术后发病率和早期死亡率影响不大;然而,糖尿病冠心病患者的长期生存率明显降低,突出了糖尿病对心血管健康的持久影响。