Suppr超能文献

血脂异常和代谢功能在2型糖尿病合并冠心病中的作用——在三级医疗中心的研究

Effect of Dyslipidaemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus - In Tertiary Care Center.

作者信息

Singh Akansha, Ambad Ranjit S, Jha Roshan Kumar

机构信息

Department of Biochemistry Jawaharlal Nehru Medical College, Sawangi (M), Wardha, Maharashtra, India.

Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (M), Wardha, Maharashtra, India.

出版信息

J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S913-S915. doi: 10.4103/jpbs.jpbs_1975_24. Epub 2025 Feb 21.

Abstract

INTRODUCTION

T2DM is strongly associated with an increased prevalence of cardiovascular disease (CVD). It has been established that CVD is the main cause of mortality among patients with type 2 diabetes mellitus (T2DM) contributing to 80% of fatal outcomes. The consistent relationship between T2DM and CVD is well-established in observational studies, meta-analyses, and has an easily discernible biological mechanism.

AIM AND OBJECTIVES

This was a cross-sectional study consisting of 100 subjects of diabetic and non-diabetic with CHD attending medicine outpatient department (OPD).

RESULT AND CONCLUSION

The study highlights that diabetes significantly exacerbates the metabolic and cardiovascular risks in coronary heart disease (CHD) patients, affecting lipid profiles, glycemic control, and long-term survival. Effective management of these parameters is crucial to improving outcomes in diabetic CHD patients. Postoperative morbidity and early mortality were not substantially affected by diabetes; however, long-term survival in diabetic CHD patients was markedly diminished, highlighting the enduring effects of diabetes on cardiovascular health.

摘要

引言

2型糖尿病(T2DM)与心血管疾病(CVD)患病率增加密切相关。已确定心血管疾病是2型糖尿病(T2DM)患者死亡的主要原因,占致命结局的80%。T2DM与CVD之间的一致性关系在观察性研究、荟萃分析中已得到充分证实,并且有易于识别的生物学机制。

目的

这是一项横断面研究,包括100名患有冠心病的糖尿病和非糖尿病患者,他们在医学门诊就诊。

结果与结论

该研究强调,糖尿病会显著加剧冠心病(CHD)患者的代谢和心血管风险,影响血脂水平、血糖控制和长期生存。有效管理这些参数对于改善糖尿病冠心病患者的预后至关重要。糖尿病对术后发病率和早期死亡率影响不大;然而,糖尿病冠心病患者的长期生存率明显降低,突出了糖尿病对心血管健康的持久影响。

相似文献

4
Dyslipidaemia in type 2 diabetes mellitus: bad for the heart.2型糖尿病中的血脂异常:对心脏有害。
Curr Opin Cardiol. 2017 Jul;32(4):422-429. doi: 10.1097/HCO.0000000000000407.

本文引用的文献

2
Complications of Diabetes 2017.2017年糖尿病并发症
J Diabetes Res. 2018 Mar 11;2018:3086167. doi: 10.1155/2018/3086167. eCollection 2018.
7
The pathologic continuum of diabetic vascular disease.糖尿病血管疾病的病理连续体
J Am Coll Cardiol. 2009 Feb 3;53(5 Suppl):S35-42. doi: 10.1016/j.jacc.2008.09.055.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验