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尺寸仍然重要吗?——后腹腔镜肾上腺切除术治疗直径>6cm肿瘤的可行性

Does size still matter? - Feasibility of posterior retroperitoneoscopic adrenalectomy for tumors >6cm.

作者信息

Feka Joy, Soliman Barbara, Arikan Melisa, Sacher Magdalena, Binter Teresa, Hargitai Lindsay, Scheuba Christian, Riss Philipp

机构信息

Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.

出版信息

Langenbecks Arch Surg. 2025 Jun 13;410(1):189. doi: 10.1007/s00423-025-03769-7.

Abstract

PURPOSE

Retroperitoneoscopic adrenalectomy (RPA) has proven to be safe and feasible with favorable postoperative courses. The role of RPA for tumor sizes larger than 6 cm is still controversial. The aim of the study was to evaluate the postoperative outcome for removal of larger adrenal tumors via the retroperitoneoscopic route.

METHODS

In this retrospective study, from 105 conducted RPA procedures, thirteen patients with adrenal tumor sizes larger than 6 cm received RPA in our hospital between January 2017 and December 2020. Clinicopathological factors, length of hospital stay, operative time and postoperative outcomes were included in this analysis.

RESULTS

From this patient cohort, six (46.15%) were female and seven (53.85%) were male with a mean age of 53.85 ± 7.89 years and a mean BMI of 28.64 ± 3.61 kg/m2, Cushing's syndrome being the most common diagnosis (53.85%). Mean lesion size was 73.31 ± 10.39 mm, tumor size varied from 60 mm up to 92 mm. Two patients (15.38%) required conversion to open laparotomy due to uncontrollable bleeding or an unclear view on the basis of adhesions. Postoperative complications were noted for one patient (7.69%), who suffered from a small superficial wound infection. Neither capsule ruptures nor mortality were documented. The median hospital stay was 3 days.

CONCLUSION

A re-evaluation of the arbitrarily placed cut-off should be discussed, since even with a slightly higher but nevertheless acceptable risk of conversion rate, RPA offers many advantages.

摘要

目的

后腹腔镜肾上腺切除术(RPA)已被证明是安全可行的,术后病程良好。RPA对于大于6 cm的肿瘤的作用仍存在争议。本研究的目的是评估通过后腹腔镜途径切除较大肾上腺肿瘤的术后结果。

方法

在这项回顾性研究中,在我们医院于2017年1月至2020年12月期间进行的105例RPA手术中,13例肾上腺肿瘤大小大于6 cm的患者接受了RPA。本分析纳入了临床病理因素、住院时间、手术时间和术后结果。

结果

在该患者队列中,女性6例(46.15%),男性7例(53.85%),平均年龄为53.85±7.89岁,平均BMI为28.64±3.61 kg/m²,库欣综合征是最常见的诊断(53.85%)。平均病变大小为73.31±10.39 mm,肿瘤大小从60 mm到92 mm不等。2例患者(15.38%)因出血无法控制或因粘连导致视野不清而需要转为开放剖腹手术。1例患者(7.69%)出现术后并发症,为小面积浅表伤口感染。未记录有包膜破裂或死亡情况。中位住院时间为3天。

结论

应讨论对任意设定的界限值进行重新评估,因为即使转化率风险略高但仍可接受,RPA仍具有许多优势。

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