Maunoury R
C R Acad Hebd Seances Acad Sci D. 1977 Mar 14;284(11):991-4.
Twelve human tumors were cultivated in vitro by the trypsinization technique and 3 cell lines were established. Each of these 3 lines showed individual characteristics which were maintained during passages. After inoculation into nude mice, 2 lines induced tumors which possessed the histologic features of the original human tumors (melanoma and carcinoma of stomach), the other line derived from a breast carcinoma was rejected.
采用胰蛋白酶消化技术对12例人类肿瘤进行体外培养，建立了3株细胞系。这3株细胞系中的每一株都表现出各自的特征，且在传代过程中得以保持。接种到裸鼠体内后，2株细胞系诱导产生的肿瘤具有原始人类肿瘤（黑色素瘤和胃癌）的组织学特征，而另一株源自乳腺癌的细胞系则被排斥。
