Otellin V A, Gilerovich E G, Gusikhina V I
Arkh Anat Gistol Embriol. 1985 Aug;89(8):18-22.
A possibility for transplanting anlages of human embryonal neocortex into mature rat brain has been studied. Light- and electron-microscopic investigations demonstrate that the embryonal tissue of the human neocortex implants into the cerebral grey and white substance of mature rats. In the grafts cellular elements proliferate and differentiate, neuropil is formed. These results open certain perspectives for modelling investigations on histogenesis of neural tissues and on studying possibilities for clinical use of grafts of the human embryonal brain.
对将人类胚胎新皮质原基移植到成年大鼠大脑中的可能性进行了研究。光镜和电镜研究表明,人类新皮质的胚胎组织植入到成年大鼠的大脑灰质和白质中。在移植组织中,细胞成分增殖并分化,形成神经毡。这些结果为神经组织组织发生的建模研究以及人类胚胎脑移植临床应用可能性的研究开辟了一定的前景。