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罕见病例报告:宫颈腺癌肝转移伴囊性肿块及梗阻性黄疸。

Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice.

作者信息

Li Jin, Wei Xin, Luo Le

机构信息

Department of Ultrasound, Deyang People's Hospital, Deyang, Sichuan, China.

Medical Records Statistics Management Section, Deyang People's Hospital, Deyang, Sichuan, China.

出版信息

Front Oncol. 2025 May 30;15:1558946. doi: 10.3389/fonc.2025.1558946. eCollection 2025.

Abstract

Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient's surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.

摘要

肝转移瘤可源自各种器官的原发性肿瘤;然而,宫颈癌转移至肝脏较为罕见。发生远处转移的宫颈癌患者预后较差,生存率降低。本报告描述了一例在宫颈腺癌切除术后四年观察到的伴有梗阻性黄疸的肝囊性肿块病例。该病变缺乏肝转移瘤的典型影像学特征,最初怀疑是胆道肿瘤。进行了超声引导下的对比增强针吸活检以确诊。组织病理学分析证实为肝腺癌,免疫组化染色提示起源于子宫或附件。考虑到患者的手术史,最终诊断为源自宫颈腺癌的肝转移。本报告回顾相关文献,以讨论宫颈癌肝转移的临床特征、诊断挑战及治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ce8/12162578/27ac56239e49/fonc-15-1558946-g001.jpg

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