Yang Shangdi, Chen Richao, Yi Mingjia, Li Chuangnan
Neurosurgery Department, Jiangmen Hospital of Traditional Chinese Medicine Affiliated to Jinan University, Jiangmen, China.
Front Pharmacol. 2025 May 30;16:1602971. doi: 10.3389/fphar.2025.1602971. eCollection 2025.
Traumatic carotid-cavernous fistulas (CCFs) are rare but potentially life-threatening vascular anomalies resulting from head trauma. Oxidative stress markedly disrupts resolution and vascular function, significantly hindering recovery.
This study presents a case series of six patients diagnosed with CCFs following traumatic events. The cases highlight the complexity of clinical presentation, imaging findings, and treatment approaches, emphasizing the role of advanced endovascular techniques in managing these conditions.
Patients underwent a combination of coil embolization, stent-assisted embolization, and balloon-assisted occlusion, demonstrating the necessity of personalized multimodal treatment strategies. Postoperative outcomes varied, with most patients achieving fistula closure and symptom stabilization, although visual impairments persisted in some cases.
This study highlights the importance of prompt diagnosis, interdisciplinary collaboration, and personalized evolving endovascular interventions in optimizing patient outcomes in traumatic CCFs.
创伤性颈内动脉海绵窦瘘(CCF)虽罕见,但因头部外伤导致的这种血管异常可能危及生命。氧化应激显著破坏血管修复和功能,严重阻碍恢复。
本研究呈现了一组6例创伤事件后诊断为CCF的病例系列。这些病例突出了临床表现、影像学表现及治疗方法的复杂性,强调了先进血管内技术在处理这些病症中的作用。
患者接受了弹簧圈栓塞、支架辅助栓塞和球囊辅助闭塞等联合治疗,表明个性化多模式治疗策略的必要性。术后结果各异,多数患者实现瘘口闭合且症状稳定,不过部分病例仍存在视力障碍。
本研究强调了及时诊断、多学科协作以及个性化且不断发展的血管内干预措施在优化创伤性CCF患者预后方面的重要性。