Croarkin Paul E, Nakonezny Paul A, Morris David W, Rush A John, Kennard Betsy D, Emslie Graham J
Mayo Clinic, Rochester, Minnesota.
UT Southwestern Medical Center in Dallas, Texas.
JAACAP Open. 2024 May 27;3(2):335-343. doi: 10.1016/j.jaacop.2024.05.002. eCollection 2025 Jun.
Current rating scales for depressive symptom severity in pediatric patients do not meet the needs of contemporary clinical practice and research. This study sought to evaluate relative performance and psychometric properties of the 5-item Brief Children's Depression Rating Scale-Revised (BCDRS-R5), as well as the clinician-rated and self-report versions of the 5-item Very Quick Inventory of Depressive Symptomatology (VQIDS-A5-C and VQIDS-A5-SR, respectively).
This study examined a sample of 165 outpatients aged 8 to 17 years with major depressive disorder who were treated openly with fluoxetine for 6 weeks from a prior National Institute of Mental Health (NIMH)-funded study. We examined the internal consistency, scale dimensionality, relative performance in detecting remission and response, and sensitivity to change of each 5-item scale.
All 3 brief scales had good-to-excellent internal consistency. Cronbach coefficient α values were 0.687 to 0.795 at baseline and 0.766 to 0.844 at week 6. Principal component analysis suggested a 1-factor solution for each scale. The BCDRS-R5 demonstrated a greater degree of accuracy in identifying response and remission compared to the VQIDS-A5-C and VQIDS-A5-SR. The scales were sensitive to change in symptom severity over 6 weeks of acute treatment with fluoxetine.
Three novel, brief scales assessing depressive symptom severity in pediatric patients showed similar performance and sensitivity to change in symptom severity over 6 weeks of acute treatment when compared with longer, standard scales.
Sequential Treatment of Pediatric MDD to Increase Remission and Prevent Relapse; https://clinicaltrials.gov/study/NCT00612313.
目前用于评估儿科患者抑郁症状严重程度的评定量表无法满足当代临床实践和研究的需求。本研究旨在评估5项儿童抑郁简易评定量表修订版（BCDRS-R5）以及5项抑郁症状快速自评量表的临床医生评定版和自我报告版（分别为VQIDS-A5-C和VQIDS-A5-SR）的相对性能和心理测量特性。
本研究选取了165名年龄在8至17岁、患有重度抑郁症的门诊患者作为样本，这些患者来自先前由美国国立精神卫生研究所（NIMH）资助的一项研究，他们接受了为期6周的氟西汀开放治疗。我们检验了每个5项量表的内部一致性、量表维度、检测缓解和反应的相对性能以及对变化的敏感性。
所有3个简易量表都具有良好至极优的内部一致性。基线时的Cronbach系数α值为0.687至0.795，第6周时为0.766至0.844。主成分分析表明每个量表均为单因素结构。与VQIDS-A5-C和VQIDS-A5-SR相比，BCDRS-R5在识别反应和缓解方面表现出更高的准确性。这些量表对氟西汀急性治疗6周期间症状严重程度的变化敏感。
与更长的标准量表相比，三种用于评估儿科患者抑郁症状严重程度的新型简易量表在急性治疗6周期间表现出相似的性能和对症状严重程度变化的敏感性。
儿科重度抑郁症序贯治疗以提高缓解率并预防复发；https://clinicaltrials.gov/study/NCT00612313 。
