Tünay Abdurrahman, Acıkgoz Alican, Atesal Özlem
Department of Anesthesiology and Reanimation, İstanbul Training and Research Hospital, University of Health Sciences Turkey, İstanbul, Turkey.
Med Sci Monit. 2025 Jun 17;31:e948228. doi: 10.12659/MSM.948228.
BACKGROUND Central venous catheterization (CVC) is a technique administered extensively for many indications, including establishing a secure stable route for drug administration, volume resuscitation, central venous pressure measurement, and facilitation of complex interventions such as oncologic treatments. In the literature, there is no evidence of a relationship between central venous lumen diameter and catheter-related thrombosis (CRT). This study aimed to evaluate the possible association between the diameter of the internal jugular vein (IJV) and the risk of CRT in 467 patients undergoing CVC. The study was conducted between April 2023 and February 2024. MATERIAL AND METHODS We assessed 467 cancer patients with a CVC inserted for chemotherapy. All patients began chemotherapy sessions after the CVC was inserted. If a catheter-associated error was detected by the oncologist, the patient was assessed by an anesthesiologist who was participating in the study. All patients were checked on the 7th day and every month until the end of the oncologic treatment to detect CRT via ultrasonography (US). RESULTS We investigated the association between thrombosis and CVP catheter axial diameter, but we did not find any association. Although the axial diameter of the thrombus group was higher than that of the non-thrombus group (14.3±3.2 mm vs 12.8±4.1 mm, p=0.104), the difference was not statistically significant. CONCLUSIONS We found that the diameter of the jugular vein was not associated with development of CRT.
中心静脉置管(CVC)是一种广泛应用于多种适应证的技术,包括建立安全稳定的给药途径、容量复苏、中心静脉压测量以及促进诸如肿瘤治疗等复杂干预措施。在文献中,没有证据表明中心静脉管腔直径与导管相关血栓形成(CRT)之间存在关联。本研究旨在评估467例行CVC的患者中颈内静脉(IJV)直径与CRT风险之间的可能关联。该研究于2023年4月至2024年2月进行。
我们评估了467例因化疗而插入CVC的癌症患者。所有患者在插入CVC后开始化疗疗程。如果肿瘤学家检测到导管相关错误,则由参与该研究的麻醉医生对患者进行评估。所有患者在第7天以及直到肿瘤治疗结束每月接受检查,通过超声检查(US)检测CRT。
我们研究了血栓形成与CVP导管轴向直径之间的关联,但未发现任何关联。尽管血栓组的轴向直径高于非血栓组(14.3±3.2 mm对12.8±4.1 mm,p = 0.104),但差异无统计学意义。
我们发现颈静脉直径与CRT的发生无关。