Department of General, Visceral and Transplant Surgery, University Hospital Münster, Waldeyerstrasse 1, 48149, Münster, Germany.
Langenbecks Arch Surg. 2021 May;406(3):903-910. doi: 10.1007/s00423-021-02097-w. Epub 2021 Feb 7.
Modern oncological treatment algorithms require a central venous device in form of a totally implantable venous access port (TIVAP). While most commonly used techniques are surgical cutdown of the cephalic vein or percutaneous puncture of the subclavian vein, there are a relevant number of patients in which an additional strategy is needed. The aim of the current study is to present a surgical technique for TIVAP implantation via an open Seldinger approach of the internal jugular vein and to characterize risk factors, associated with primary failure as well as short- (< 30 days) and long-term (> 30 days) complications.
A total of 500 patients were included and followed up for 12 months. Demographic and intraoperative data and short- as well as long-term complications were extracted. Primary endpoint was TIVAP removal due to complication. Logistic regression analysis was used to analyze associated risk factors.
Surgery was primarily successful in all cases, while success was defined as functional (positive aspiration and infusion test) TIVAP which was implanted via open Seldinger approach of the jugular vein at the intended site. TIVAP removal due to complications during the 1st year occurred in 28 cases (5.6%) while a total of 4 (0.8%) intraoperative complications were noted. Rates for short- and long-term complications were 0.8% and 6.6%, respectively.
While the presented technique requires relatively long procedure times, it is a safe and reliable method for TIVAP implantation. Our results might help to further introduce the presented technique as a secondary approach in modern TIVAP surgery.
现代肿瘤治疗方案需要一种中央静脉装置,即完全植入式静脉输液港(TIVAP)。最常用的技术通常是头静脉切开或锁骨下静脉经皮穿刺,但仍有相当一部分患者需要采用其他策略。本研究旨在介绍一种通过颈内静脉切开术行 TIVAP 植入的手术技术,并分析与主要失败以及短期(<30 天)和长期(>30 天)并发症相关的风险因素。
共纳入 500 例患者并进行了 12 个月的随访。提取了人口统计学和术中数据以及短期和长期并发症。主要终点是因并发症而拔除 TIVAP。采用逻辑回归分析来分析相关的风险因素。
所有病例的手术均获得了初步成功,成功定义为通过颈内静脉切开术在预期部位成功植入具有功能(抽吸和输注试验阳性)的 TIVAP。在第 1 年内,有 28 例(5.6%)因并发症而拔除 TIVAP,共有 4 例(0.8%)术中并发症。短期和长期并发症的发生率分别为 0.8%和 6.6%。
虽然该技术的手术时间相对较长,但它是一种安全可靠的 TIVAP 植入方法。我们的研究结果可能有助于进一步将该技术作为现代 TIVAP 手术的次要方法引入。