de Sanctis Pecora Carla, Corduff Niamh, Carroll Julia, Muniz Mariana, Sattler Sonja
From the Clínica Dermatologie, São Paulo, Brazil.
Private Practice, Geelong, Australia.
Plast Reconstr Surg Glob Open. 2025 Jun 16;13(6):e6873. doi: 10.1097/GOX.0000000000006873. eCollection 2025 Jun.
Facial aging is a complex process that varies by facial layer and patient characteristics. Correction of the signs of facial aging can be achieved with various aesthetic treatments, including Cohesive Polydensified Matrix hyaluronic acid (CPM-HA), calcium hydroxylapatite in carboxymethylcellulose (CaHA-CMC), microfocused ultrasound with visualization (MFU-V), and incobotulinumtoxinA (incoBoNT-A). This article describes how these treatments can be used in an individualized, layered approach for whole-face rejuvenation that optimizes outcomes and patient satisfaction.
An international panel of 5 expert aesthetic physicians convened to align on best practices for a layered approach to whole-face rejuvenation using CPM-HA, CaHA-CMC, MFU-V, and incoBoNT-A. Panelists reviewed statements about facial aging and key features of the select products supporting their use in a layered treatment plan.
The proposed layered treatment plan expands on previous work by de Sanctis Pecora and consists of targeting (1) bone and retaining ligaments; (2) muscles, ligaments, and the superficial muscular aponeurotic system; (3) fat pads; (4) the dermis; and (5) skin quality. Panelists agreed that key features of the select products inform their positioning in the layered treatment plan. Step-by-step procedures for targeting each layer-including product, injection or application technique, and/or rationale-are provided.
CPM-HA, CaHA-CMC, MFU-V, and incoBoNT-A are considered by the expert panel of aesthetic physicians to be ideal treatment options to obtain a synergistic effect in layered whole-face rejuvenation.
面部老化是一个复杂的过程，因面部层次和患者特征而异。可通过多种美容治疗来改善面部老化迹象，包括凝聚性多密度基质透明质酸（CPM-HA）、羧甲基纤维素钙羟基磷灰石（CaHA-CMC）、可视化微聚焦超声（MFU-V）和注射用A型肉毒毒素（incoBoNT-A）。本文介绍了如何将这些治疗方法以个体化的分层方式用于全脸年轻化，从而优化治疗效果和患者满意度。
由5位国际美容专家组成的小组召开会议，就使用CPM-HA、CaHA-CMC、MFU-V和incoBoNT-A进行全脸分层年轻化治疗的最佳实践达成一致。小组成员审查了有关面部老化的陈述以及所选产品在分层治疗方案中的关键特性。
所提议的分层治疗方案在德桑蒂斯·佩科拉之前的工作基础上进行了扩展，包括针对（1）骨骼和保留韧带；（2）肌肉、韧带和浅表肌肉腱膜系统；（3）脂肪垫；（4）真皮；以及（5）皮肤质量。小组成员一致认为，所选产品的关键特性决定了它们在分层治疗方案中的定位。提供了针对每一层的分步操作程序，包括产品、注射或应用技术以及/或原理。
美容专家小组认为CPM-HA、CaHA-CMC、MFU-V和incoBoNT-A是在全脸分层年轻化中获得协同效应的理想治疗选择。
