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再生美学的发展领域。

The evolving field of regenerative aesthetics.

作者信息

Goldie Katherine

机构信息

Clinic 77 Ltd, London, UK.

出版信息

J Cosmet Dermatol. 2023 Mar;22 Suppl 1:1-7. doi: 10.1111/jocd.15556.

Abstract

BACKGROUND

Regenerative aesthetics (RA) is an emerging subfield based on many of the principles of regenerative medicine (RM). In order to ensure that the development of regenerative aesthetics is based on accepted regenerative concepts and to optimize treatment strategies, it is important to establish clear definitions, fundamental aims and consider the impact of the predominant RA tissue environment RM focuses on the regeneration of injured or diseased tissue, while RA aims to restore youthful properties to aging, senescent tissue. The distinction is key in understanding how best to develop treatments for these different goals.

AIMS AND METHODS

The current review suggests key concepts, definitions, and foundations of regenerative aesthetic approaches and examines current evidence supporting this. It considers the importance of the aging tissue environment, the essential regenerative goals of restored tissue structure and function and introduces the concept of regenerative scaffolds with a focus on CaHA. Current techniques in the field and promising future directions are also discussed.

CONCLUSION

Regenerative aesthetics is an evolving subfield of regenerative medicine. Establishing clear definitions, identifying the challenges of the aging soft tissue environment and re-evaluating current evidence in light of regenerative goals are vital for the continuing evolution of this medical field.

摘要

背景

再生美学(RA)是基于再生医学(RM)的许多原则而新兴的一个子领域。为确保再生美学的发展基于公认的再生概念并优化治疗策略,明确定义、确立基本目标并考虑主要的RA组织环境的影响至关重要。RM专注于损伤或患病组织的再生,而RA旨在使老化、衰老的组织恢复年轻特性。这种区别对于理解如何最好地针对这些不同目标开发治疗方法至关重要。

目的与方法

本综述提出了再生美学方法的关键概念、定义和基础,并审视了支持这一点的现有证据。它考虑了老化组织环境的重要性、恢复组织结构和功能的基本再生目标,并引入了以羟基磷灰石钙(CaHA)为重点的再生支架概念。还讨论了该领域的当前技术和有前景的未来方向。

结论

再生美学是再生医学中一个不断发展的子领域。明确界定、识别老化软组织环境的挑战并根据再生目标重新评估现有证据,对于该医学领域的持续发展至关重要。

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