Rustom David H, Restum Alexander A, Henry Kevin F
Pain Management, Wayne State University Detroit Medical Center, Detroit, USA.
Medical Education, Wayne State University School of Medicine, Detroit, USA.
Cureus. 2025 May 16;17(5):e84229. doi: 10.7759/cureus.84229. eCollection 2025 May.
Introduction Lumbar facet arthropathy (LFA) is a chronic degenerative condition that evolves over time. Osteoarthritis is defined by bony overgrowth, joint effusions, and synovial cysts. These findings are also seen in LFA, as there is degeneration of the facet joints throughout the spine. It primarily affects individuals >40 years of age and is a leading cause of low back pain. The most affected region of the lumbar spine includes the L4/L5 and L5/sacral ala junctions. We investigated the association between lumbar medial branch blocks (LMBBs) and radiofrequency ablations (RFAs), and the reduction in prescription opioid use in patients with LFA. Methods This is a retrospective cohort study of patients presenting to an outpatient pain medicine clinic with documented LFA. A total of 526 patients with LFA who underwent an LMBB, RFA, or a combination of both procedures were evaluated for morphine-equivalent opioid prescriptions in the outpatient clinic before and after the interventions. We used a paired t-test to compare pre- and post-procedure results to assess changes in prescribed morphine equivalent medications. Results There were statistically significant reductions in prescription opioid use when standardized to morphine equivalency in patients who underwent an LMBB or a combination of both LMBB and RFA procedures. For patients who underwent an LMBB procedure, the mean reduction in opioid equivalence dose from pre- to post-procedure was 4.06 mg. Among those who received both LMBB and RFA, the reduction was 6.10 mg, suggesting that the addition of RFA may further enhance the decrease in opioid use. Conclusions We found that individuals who underwent an LMBB or a combination of LMBB and RFA procedures had a significant reduction in morphine-equivalent drug use within the outpatient pain medicine clinic. These findings support the effectiveness of these procedures in reducing pain from LFA and highlight their potential to lessen the associated healthcare burden.
引言
腰椎小关节病(LFA)是一种随时间发展的慢性退行性疾病。骨关节炎的定义是骨质增生、关节积液和滑膜囊肿。这些表现也见于LFA,因为整个脊柱的小关节都会发生退变。它主要影响40岁以上的人群,是下腰痛的主要原因。腰椎最易受累的区域包括L4/L5和L5/骶骨翼交界处。我们研究了腰椎内侧支阻滞(LMBB)和射频消融(RFA)之间的关联,以及LFA患者处方阿片类药物使用的减少情况。
方法
这是一项对到门诊疼痛医学诊所就诊且有LFA记录的患者进行的回顾性队列研究。共有526例接受LMBB、RFA或两种手术联合治疗的LFA患者在干预前后在门诊接受了吗啡等效阿片类药物处方评估。我们使用配对t检验比较手术前后的结果,以评估处方吗啡等效药物的变化。
结果
在接受LMBB或LMBB与RFA联合手术的患者中,当以吗啡等效量标准化时,处方阿片类药物的使用有统计学意义的减少。对于接受LMBB手术的患者,从术前到术后阿片类等效剂量的平均减少量为4.06毫克。在接受LMBB和RFA联合治疗的患者中,减少量为6.10毫克,这表明添加RFA可能进一步增强阿片类药物使用的减少。
结论
我们发现,接受LMBB或LMBB与RFA联合手术的患者在门诊疼痛医学诊所内吗啡等效药物的使用有显著减少。这些发现支持了这些手术在减轻LFA疼痛方面的有效性,并突出了它们减轻相关医疗负担的潜力。