Abdullah Ari M, Ahmed Shaho F, Ali Rawa M, Qaradakhy Aras J, Salih Abdulwahid M, Muhialdeen Aso S, Dhahir Hardi M, Qadir Abdullah A, Hassan Shko H, Kakamad Fahmi H
Scientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaymaniyah 46001, Iraq.
Department of Pathology, Sulaymaniyah Teaching Hospital, Zanko Street, Sulaymaniyah 46001, Iraq.
J Surg Case Rep. 2025 Jun 16;2025(6):rjaf389. doi: 10.1093/jscr/rjaf389. eCollection 2025 Jun.
Synchronous medullary and papillary thyroid carcinoma (MTC-PTC) is rare, particularly with metastasis to the same lymph node. This study presents a unique case of synchronous metastatic MTC and PTC in a single lymph node. A 35-year-old male presented with a neck swelling, diagnosed with MTC-PTC. Imaging revealed thyroid nodules, and histopathological examination following thyroidectomy confirmed mixed MTC-PTC with lymph node metastasis. Literature reports similar cases in patients aged 24-64, often presenting with neck lumps. Management typically involves total thyroidectomy with lymph node dissection, yielding favorable outcomes. Treatment should follow guidelines based on disease stage. Due to its rarity, further research is needed to better understand and manage this condition.
同步性甲状腺髓样癌和乳头状癌（MTC-PTC）很罕见，尤其是转移至同一淋巴结的情况。本研究报告了一例独特的同步性转移性MTC和PTC发生于单个淋巴结的病例。一名35岁男性因颈部肿胀就诊，被诊断为MTC-PTC。影像学检查发现甲状腺结节，甲状腺切除术后的组织病理学检查证实为混合性MTC-PTC伴淋巴结转移。文献报道了年龄在24至64岁的类似病例，通常表现为颈部肿块。治疗通常包括全甲状腺切除术及淋巴结清扫术，预后良好。治疗应遵循基于疾病分期的指南。由于其罕见性，需要进一步研究以更好地了解和处理这种情况。
