Saalman E
Biomaterials. 1985 Jul;6(4):225-30. doi: 10.1016/0142-9612(85)90017-1.
Fourier transform infrared spectroscopy has been used to study thin polymer films exposed to ethylene oxide (EO). The i.r. technique represents a new way of studying this subject. The polymers studied were poly(vinyl chloride), polyethylene and polystyrene. They were exposed to EO, either in a small commercial EO-sterilizer which uses pure EO and operates at subatmospheric pressure, at a temperature of 37 or 55 degrees C, or under experimental laboratory conditions. The absorption and diffusion of EO in the polymers was studied. Potential reaction products, such as ethylene glycol and ethylene chlorohydrin, were looked for but could not be traced. The detection limit of the method was 1 ppm (microgram/g) EO. Typical spectra of the polymer films, before and after exposure to EO, are shown. Diffusion coefficients for poly(vinyl chloride) and polyethylene have been calculated.
傅里叶变换红外光谱法已被用于研究暴露于环氧乙烷（EO）的聚合物薄膜。红外技术代表了研究该主题的一种新方法。所研究的聚合物为聚氯乙烯、聚乙烯和聚苯乙烯。它们在小型商用环氧乙烷灭菌器中暴露于环氧乙烷，该灭菌器使用纯环氧乙烷，在低于大气压的压力下，于37或55摄氏度的温度下运行，或者在实验室内条件下进行。研究了环氧乙烷在聚合物中的吸收和扩散。寻找了潜在的反应产物，如乙二醇和氯乙醇，但未检测到。该方法的检测限为1 ppm（微克/克）环氧乙烷。展示了聚合物薄膜在暴露于环氧乙烷之前和之后的典型光谱。计算了聚氯乙烯和聚乙烯的扩散系数。
