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[过敏性肺炎:放射学视角的S2K指南]

[Hypersensitivity pneumonitis : S2K guideline from a radiological perspective].

作者信息

Hamer Okka W, Koschel Dirk, Rehbock Beate

机构信息

Institut für Röntgendiagnostik, Universitätsklinikum Regensburg und Lungenfachklinik Caritas St. Maria, Donaustauf, Deutschland.

Abteilung Innere Medizin und Pneumologie, Fachkrankenhaus Coswig, Lungenzentrum, Coswig und Bereich Pneumologie, Medizinische Klinik 1, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Deutschland.

出版信息

Radiologie (Heidelb). 2025 Jun 17. doi: 10.1007/s00117-025-01461-x.

DOI:10.1007/s00117-025-01461-x
PMID:40526330
Abstract

Hypersensitivity pneumonitis (HP, also known as extrinsic allergic alveolitis [EAA]) is a rare disease which is limited to the lungs and caused by an immunological inflammatory reaction of the lung parenchyma and terminal bronchioli. The first German guideline on the diagnosis and treatment of HP was published in 2024. The imaging method of choice is high-resolution computed tomography (HRCT). Radiologically, a distinction is made between purely inflammatory and fibrotic HP. If there are signs of fibrotic HP in the HRCT, the relation between the extent of inflammation and fibrosis should be determined and given in the report. The prognosis depends significantly on the extent of fibrosis and the proportion of so-called honeycombs.

摘要

过敏性肺炎(HP,也称为外源性过敏性肺泡炎 [EAA])是一种罕见疾病,仅限于肺部,由肺实质和终末细支气管的免疫炎症反应引起。德国首部关于HP诊断和治疗的指南于2024年发布。首选的成像方法是高分辨率计算机断层扫描(HRCT)。在放射学上,可区分单纯炎症性和纤维化性HP。如果HRCT中有纤维化性HP的迹象,应确定炎症和纤维化程度之间的关系并在报告中给出。预后很大程度上取决于纤维化程度和所谓蜂窝状结构的比例。

相似文献

1
[Hypersensitivity pneumonitis : S2K guideline from a radiological perspective].[过敏性肺炎:放射学视角的S2K指南]
Radiologie (Heidelb). 2025 Jun 17. doi: 10.1007/s00117-025-01461-x.
2
Chronic hypersensitivity pneumonitis or idiopathic pulmonary fibrosis? Diagnostic role of high resolution Computed Tomography (HRCT).慢性过敏性肺炎还是特发性肺纤维化?高分辨率计算机断层扫描(HRCT)的诊断作用。
Radiol Med. 2003 Sep;106(3):135-46.
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The new useful high-resolution computed tomography finding for diagnosing fibrotic hypersensitivity pneumonitis: "hexagonal pattern": a single-center retrospective study.用于诊断纤维化型过敏性肺炎的新的有用高分辨率计算机断层扫描发现:“六边形状”:一项单中心回顾性研究。
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Computed tomography in hypersensitivity pneumonitis: main findings, differential diagnosis and pitfalls.高分辨率 CT 在过敏性肺炎中的应用:主要发现、鉴别诊断和误区。
Expert Rev Respir Med. 2018 Jan;12(1):5-13. doi: 10.1080/17476348.2018.1395282. Epub 2017 Oct 26.
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[Diagnosis and Treatment of Hypersensitivity Pneumonitis - S2k Guideline of the German Respiratory Society and the German Society for Allergology and Clinical Immunology].[过敏性肺炎的诊断与治疗——德国呼吸学会和德国变态反应与临床免疫学会S2k指南]
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[Hypersensitivity Pneumonitis - an important differential diagnosis of infiltrative lung diseases].[过敏性肺炎——浸润性肺疾病的重要鉴别诊断]
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Features of transbronchial lung cryobiopsy-diagnosed fibrotic hypersensitivity pneumonitis.经支气管肺冷冻活检诊断的纤维化过敏性肺炎的特征。
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本文引用的文献

1
[Diagnosis and Treatment of Hypersensitivity Pneumonitis - S2k Guideline of the German Respiratory Society and the German Society for Allergology and Clinical Immunology].[过敏性肺炎的诊断与治疗——德国呼吸学会和德国变态反应与临床免疫学会S2k指南]
Pneumologie. 2024 Dec;78(12):963-1002. doi: 10.1055/a-2369-8458. Epub 2024 Sep 3.
2
Fleischner Society: Glossary of Terms for Thoracic Imaging.美国胸科学会:胸部影像学术语词汇表。
Radiology. 2024 Feb;310(2):e232558. doi: 10.1148/radiol.232558.
3
Development of a Knowledge-sharing Website for Hypersensitivity Pneumonitis Exposures.
用于过敏性肺炎暴露的知识共享网站的开发。
ATS Sch. 2022 Sep 30;3(3):460-467. doi: 10.34197/ats-scholar.2021-0139IN. eCollection 2022 Oct.
4
Mosaic attenuation in non-fibrotic areas as a predictor of non-usual interstitial pneumonia pathologic diagnosis.非纤维化区域马赛克衰减作为非寻常型间质性肺炎病理诊断的预测因子。
Sci Rep. 2022 May 4;12(1):7289. doi: 10.1038/s41598-022-10750-7.
5
Incidence and Prevalence of Children's Diffuse Lung Disease in Spain.西班牙儿童弥漫性肺部疾病的发病率和患病率
Arch Bronconeumol. 2022 Jan;58(1):22-29. doi: 10.1016/j.arbres.2021.06.001. Epub 2021 Jun 17.
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Hypersensitivity pneumonitis: Lessons from a randomized controlled trial in children.过敏性肺炎:一项儿童随机对照试验的教训。
Pediatr Pulmonol. 2021 Aug;56(8):2627-2633. doi: 10.1002/ppul.25513. Epub 2021 May 28.
7
Hypersensitivity pneumonitis.过敏性肺炎。
Nat Rev Dis Primers. 2020 Aug 6;6(1):65. doi: 10.1038/s41572-020-0191-z.
8
Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline.成人过敏性肺炎的诊断。美国胸科学会/日本呼吸学会/拉丁美洲胸科学会临床实践指南。
Am J Respir Crit Care Med. 2020 Aug 1;202(3):e36-e69. doi: 10.1164/rccm.202005-2032ST.
9
Variable utility of mosaic attenuation to distinguish fibrotic hypersensitivity pneumonitis from idiopathic pulmonary fibrosis.马赛克衰减在鉴别纤维化型过敏性肺炎与特发性肺纤维化中的可变效用。
Eur Respir J. 2019 Jul 25;54(1). doi: 10.1183/13993003.00531-2019. Print 2019 Jul.
10
CT Phenotypes in Hypersensitivity Pneumonitis.过敏性肺炎的CT表型
Chest. 2019 Apr;155(4):655-656. doi: 10.1016/j.chest.2018.10.048.