Matsumura K, Nakayama T, Tamaki Y
Brain Res. 1985 Nov 4;346(2):327-32. doi: 10.1016/0006-8993(85)90866-2.
In anesthetized rats, the effect of preoptic-hypothalamic thermal stimulation was studied on supraoptic neurosecretory cells identified antidromically. More than 70% of the supraoptic neurons responded to preoptic-hypothalamic thermal stimulation in two different manners. Forty-five percent of these responding neurons increased and decreased their firing activities during rise and fall in preoptic temperature, respectively, and did not show any transient alteration in the activities. The remaining 55% transiently altered firing activities during change in temperature, but the activity depended on level of the temperature in the steady state. In almost all neurons of either type, averaged firing rates were minimal at preoptic-hypothalamic temperatures below 36 degrees C and maximal at temperatures above 39 degrees C. In 73% of the thermally responsive neurons, firing rate changed simultaneously with arterial blood pressure. In the remaining 27%, however, neuronal responses were observed without any fluctuation in the blood pressure. These results suggest that activities of the supraoptic neurosecretory cells are influenced by brain temperature.
在麻醉大鼠中，研究了视前区 - 下丘脑热刺激对经逆向鉴定的视上神经分泌细胞的影响。超过70%的视上神经元以两种不同方式对视前区 - 下丘脑热刺激产生反应。这些反应性神经元中，45%在视前区温度上升和下降期间分别增加和降低其放电活动，并且在活动中未显示任何瞬时改变。其余55%在温度变化期间瞬时改变放电活动，但活动取决于稳定状态下的温度水平。在几乎所有两种类型的神经元中，平均放电率在视前区 - 下丘脑温度低于36℃时最小，在高于39℃时最大。在73%的热反应性神经元中，放电率与动脉血压同时变化。然而，在其余27%中，观察到神经元反应时血压没有任何波动。这些结果表明，视上神经分泌细胞的活动受脑温影响。
