Gupta Kaustubh, Singh Neha, Raj Gaurav, Kumar Yogesh, Kumar Akshay
Department of Radio-Diagnosis, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Radiol Case Rep. 2025 Jun 6;20(9):4215-4220. doi: 10.1016/j.radcr.2025.05.012. eCollection 2025 Sep.
Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder characterized by multisystem hamartomatous growths. Clinical manifestations are diverse, and prognosis varies depending on the affected organs. Diagnosis typically involves genetic testing or clinical diagnostic criteria. We report the case of a 39-year-old female with multiple manifestations of TSC, highlighting the uncommon occurrence of multifocal micronodular pneumocyte hyperplasia (MMPH) and splenic hamartomas, emphasizing their clinical significance and diagnostic considerations.
结节性硬化症（TSC）是一种罕见的常染色体显性疾病，其特征为多系统错构瘤样生长。临床表现多样，预后因受累器官而异。诊断通常需要进行基因检测或依据临床诊断标准。我们报告了一名39岁患有多种TSC表现的女性病例，突出了多灶性微小结节性肺细胞增生（MMPH）和脾错构瘤的罕见发生情况，强调了它们的临床意义和诊断注意事项。
