Badi Safaa, Suliman Sara Zainelabdein, Almahdi Rayan, Aldomah Mohammed A, Elkheir Habab Khalid, Ibrahim Mohamed Izham Mohamed, Ahmed Mohamed H
Department of Clinical Pharmacy, Faculty of Pharmacy, Omdurman Islamic University, Khartoum 14415, Sudan.
Department of Clinical Pharmacy, University of Science and Technology, Khartoum 14411, Sudan.
Explor Res Clin Soc Pharm. 2025 May 27;19:100617. doi: 10.1016/j.rcsop.2025.100617. eCollection 2025 Sep.
Diabetes affects various body systems, increasing the risk of complications.
This study assessed the impact of clinical pharmacist-associated education on diabetes self-care practices and glycemic control in Sudanese individuals with Type 2 Diabetes Mellitus (T2DM).
This quasi-experimental study with no control group recruited 110 adults with T2DM from a diabetes clinic over 12 months using simple random sampling. We collected data through interviews and calls. Participants received 12 educational videos covering diabetes management. The intervention was video-based and delivered over 5 months. We analyzed data using SPSS version 28.
The mean age of participants was 56.2 ± 10.3 years. Self-care practices significantly improved over time. Fasting blood glucose (FBG) levels decreased by 16.7 mg/dL at 6 months ( = 0.009) and 41.9 mg/dL at 12 months ( < 0.001). Two-hour postprandial glucose levels dropped by 18.7 mg/dL at 6 months ( = 0.006) and 61.8 mg/dL at 12 months ( < 0.001). HbA1c levels decreased by 1 % at6 months ( < 0.001) and 1.9 % at 12 months ( < 0.001). The effect size (Cohen's d) was increased from 0.26 at 6 months to 0.74 at 12 months. Similarly, it was increased for 2hrsPPG from 0.2 at 6 months to 0.74 at 12 months. For HbA1c, it was increased from 0.62 at 6 months to 1.25 at 12 months, indicating clinically meaningful improvement in long-term glycemic control following the pharmacist intervention. LDL decreased by 9.2 mg/dL at 12 months ( < 0.001), and HDL increased by 5.5 mg/dL at 12 months ( = 0.002). Changes in BUN and serum creatinine were insignificant.
Clinical pharmacist education improved diabetes self-care practices and metabolic outcomes, including glycemic control and lipid profiles, demonstrating its role in achieving therapeutic goals for patients with T2DM.
糖尿病会影响身体各个系统,增加并发症风险。
本研究评估了临床药师相关教育对苏丹2型糖尿病(T2DM)患者糖尿病自我护理实践和血糖控制的影响。
本无对照组的准实验研究在12个月内通过简单随机抽样从一家糖尿病诊所招募了110名成年T2DM患者。我们通过访谈和电话收集数据。参与者观看了12个关于糖尿病管理的教育视频。干预基于视频,为期5个月。我们使用SPSS 28版分析数据。
参与者的平均年龄为56.2±10.3岁。随着时间推移,自我护理实践显著改善。空腹血糖(FBG)水平在6个月时下降了16.7mg/dL(P = 0.009),在12个月时下降了41.9mg/dL(P<0.001)。餐后两小时血糖水平在6个月时下降了18.7mg/dL(P = 0.006),在12个月时下降了61.8mg/dL(P<0.001)。糖化血红蛋白(HbA1c)水平在6个月时下降了1%(P<0.001),在12个月时下降了1.9%(P<0.001)。效应量(科恩d值)从6个月时的0.26增加到12个月时的0.74。同样,餐后两小时血糖的效应量从6个月时的0.2增加到12个月时的0.74。对于HbA1c,从6个月时的0.62增加到12个月时的1.25,表明药师干预后长期血糖控制有临床意义的改善。低密度脂蛋白(LDL)在12个月时下降了9.2mg/dL(P<0.001),高密度脂蛋白(HDL)在12个月时增加了5.5mg/dL(P = 0.002)。尿素氮(BUN)和血清肌酐的变化不显著。
临床药师教育改善了糖尿病自我护理实践和代谢结果,包括血糖控制和血脂谱,证明了其在实现T2DM患者治疗目标中的作用。