Alqarni Saleha, Alsaeedi Eatedal Eenizan, Siraj Rayan A, Aldabayan Yousef Saad, Abdelhafez Amal Ismael
Department of Clinical Nutrition, College of Applied Medical Sciences, King Faisal University, Al Ahsa, Saudi Arabia.
Department of Clinical Nutrition, College of Applied Medical Sciences, University of Hafr Al Batin, Hafr Al Batin, Saudi Arabia.
Front Nutr. 2025 Jun 3;12:1558151. doi: 10.3389/fnut.2025.1558151. eCollection 2025.
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent inflammation and airflow limitation. The ketogenic diet (KD), recognized for its anti-inflammatory properties, has potential therapeutic benefits for COPD management. However, healthcare professionals' perceptions of KD's efficacy and applicability in COPD care remain underexplored, particularly in Saudi Arabia.
A cross-sectional online survey was conducted between June and September 2024, targeting healthcare professionals involved in COPD management. The survey evaluated perceptions of KD's benefits, limitations, and current nutritional practices. Descriptive statistics and logistic regression analyses were performed using JASP to identify predictors of KD training uptake and the likelihood of discussing dietary interventions with COPD patients.
A total of 1,068 healthcare professionals participated in the survey. Of these, 58% believed KD could improve quality of life in COPD patients, and 61% acknowledged its potential to reduce inflammation. Logistic regression identified familiarity with KD as significant predictor for receiving KD training ( < 0.001). Concerns regarding KD's adverse effects, such as constipation and dehydration, were noted by 76% of respondents. Only 14% reported recommending KD, citing insufficient evidence and lack of professional training as primary barriers. Additionally, 74% highlighted patient adherence challenges due to KD's restrictive nature and potential side effects.
KD shows promise as a complementary therapy for COPD by modulating inflammation and improving symptom management. Addressing barriers such as limited evidence and inadequate professional training is essential. Further research is required to establish the efficacy and safety of KD in COPD care.
慢性阻塞性肺疾病（COPD）是一种进行性呼吸系统疾病，其特征为持续炎症和气流受限。生酮饮食（KD）因其抗炎特性而受到认可，对COPD的管理具有潜在治疗益处。然而，医疗保健专业人员对KD在COPD护理中的疗效和适用性的看法仍未得到充分探索，尤其是在沙特阿拉伯。
于2024年6月至9月进行了一项横断面在线调查，目标是参与COPD管理的医疗保健专业人员。该调查评估了对KD益处、局限性和当前营养实践的看法。使用JASP进行描述性统计和逻辑回归分析，以确定KD培训接受度的预测因素以及与COPD患者讨论饮食干预的可能性。
共有1068名医疗保健专业人员参与了调查。其中，58%的人认为KD可以改善COPD患者的生活质量，61%的人承认其有减轻炎症的潜力。逻辑回归确定对KD的熟悉程度是接受KD培训的重要预测因素（<0.001）。76%的受访者指出了对KD不良反应的担忧，如便秘和脱水。只有14%的人报告推荐KD，称证据不足和缺乏专业培训是主要障碍。此外，74%的人强调由于KD的限制性性质和潜在副作用，患者依从性存在挑战。
KD通过调节炎症和改善症状管理，有望成为COPD的辅助治疗方法。解决证据有限和专业培训不足等障碍至关重要。需要进一步研究以确定KD在COPD护理中的疗效和安全性。
