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冯·迈耶伯格复合体:局灶性结节性增生样病变的一个未被充分认识的易感因素。

Von Meyerberg Complexes: An Underrecognized Predisposing Factor for Focal Nodular Hyperplasia-Like Lesions.

作者信息

Rastogi Ruchi, Aggarwal Bharat, Gupta Subhash, Agarwal Komal, Chugh Bhuvan

机构信息

Department of Radiology, Max Superspeciality Hospital, New Delhi, India.

Centre for Liver and Biliary Sciences, Max Superspeciality Hospital, New Delhi, India.

出版信息

Indian J Radiol Imaging. 2024 Dec 28;35(3):466-469. doi: 10.1055/s-0044-1801266. eCollection 2025 Jul.

DOI:10.1055/s-0044-1801266
PMID:40529978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12169933/
Abstract

Von Meyerberg complexes (VMCs), also termed as biliary hamartomas, are common ductal plate malformations and are considered as benign incidental findings. These are occasionally discovered in histopathological examination or on imaging in individuals being investigated for an unrelated issue and do not warrant any active intervention. However, it is important to recognize that sometimes VMCs can predispose to malignant masses or rarely to hypervascular benign masses as in present case, causing diagnostic dilemma.

摘要

冯·迈耶贝格复合体(VMCs),也被称为胆管错构瘤,是常见的导管板畸形,被认为是良性偶然发现。这些病变偶尔在组织病理学检查中或在因无关问题接受检查的个体的影像学检查中被发现,无需任何积极干预。然而,重要的是要认识到,有时VMCs可能易患恶性肿块,或如本例中罕见地易患高血供良性肿块,从而导致诊断困境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/63722266bf24/10-1055-s-0044-1801266-i2484013-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/72c2b4323f32/10-1055-s-0044-1801266-i2484013-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/8827d66a94f5/10-1055-s-0044-1801266-i2484013-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/63722266bf24/10-1055-s-0044-1801266-i2484013-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/72c2b4323f32/10-1055-s-0044-1801266-i2484013-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/8827d66a94f5/10-1055-s-0044-1801266-i2484013-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/12169933/63722266bf24/10-1055-s-0044-1801266-i2484013-3.jpg

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本文引用的文献

1
Multiple Biliary Hamartomas, The ''Von Meyenburg Complexes''.多发性胆管错构瘤,即“冯·迈恩伯格复合体”
Ann Hepatol. 2017 Sep-Oct;16(5):812-813. doi: 10.5604/01.3001.0010.2822.
2
Pediatric living donor liver transplantation for congenital hepatic fibrosis using a mother's graft with von Meyenburg complex: A case report.小儿先天性肝纤维化活体肝移植:使用母亲带有梅氏复合体的移植物的病例报告
World J Gastroenterol. 2016 Nov 28;22(44):9865-9870. doi: 10.3748/wjg.v22.i44.9865.
3
Malignant Transformation in Von-Meyenburg Complexes: Histologic and Immunohistochemical Clues With Illustrative Cases.
冯·迈恩伯格复合体中的恶性转化:组织学和免疫组织化学线索及病例说明
Appl Immunohistochem Mol Morphol. 2015 Oct;23(9):607-14. doi: 10.1097/PAI.0000000000000132.
4
Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation.多发性胆管错构瘤:磁共振特征与组织病理学对照
Eur Radiol. 2008 Mar;18(3):493-9. doi: 10.1007/s00330-007-0790-z. Epub 2007 Oct 13.
5
Intraductal papillary cholangiocarcinoma associated with von Meyenberg complexes: a case report.与梅耶尔恩伯格复合体相关的导管内乳头状胆管癌:一例报告。
Dig Dis Sci. 2007 Oct;52(10):2643-5. doi: 10.1007/s10620-007-9777-5. Epub 2007 Mar 30.
6
Bile duct hamartomas (von Mayenburg complexes) mimicking liver metastases from bile duct cancer: MRC findings.酷似胆管癌肝转移的胆管错构瘤(冯·迈嫩贝格复合体):磁共振成像(MRC)表现
World J Gastroenterol. 2006 Feb 28;12(8):1321-3. doi: 10.3748/wjg.v12.i8.1321.
7
Evidence for the neoplastic transformation of Von-Meyenburg complexes.肝内胆管错构瘤发生肿瘤性转化的证据。
Am J Surg Pathol. 2000 Aug;24(8):1131-9. doi: 10.1097/00000478-200008000-00011.
8
A case with intrahepatic double cancer: hepatocellular carcinoma and cholangiocarcinoma associated with multiple von Meyenburg complexes.一例肝内双癌病例:肝细胞癌和胆管癌伴多发梅耶尔堡复合体。
Yonsei Med J. 1999 Oct;40(5):506-9. doi: 10.3349/ymj.1999.40.5.506.
9
Adenocarcinoid of the liver arising within an area of hamartoma with predominant bile duct component.起源于以胆管成分占主导的错构瘤区域内的肝脏腺类癌。
J Clin Gastroenterol. 1996 Sep;23(2):145-51. doi: 10.1097/00004836-199609000-00018.
10
The hepatic von Meyenburg complex: prevalence and association with hepatic and renal cysts among 2843 autopsies [corrected].肝脏von Meyenburg复合体:2843例尸检中其患病率及与肝囊肿和肾囊肿的关联[校正后]
Mod Pathol. 1996 Mar;9(3):233-7.