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通过整合卷积神经网络(CNN)和Swin视觉变换器,利用T1加权磁共振成像对阿尔茨海默病进行识别和诊断。

Recognition and diagnosis of Alzheimer's Disease using T1-weighted magnetic resonance imaging via integrating CNN and Swin vision transformer.

作者信息

Wang Yanlei, Sheng Hui, Wang Xueling

机构信息

Shandong University of Political Science and Law, Jinan, 250000, Shandong, China.

Department of Radiology, Yantaishan Hospital, Yantai, 264000, Shandong, China.

出版信息

Clinics (Sao Paulo). 2025 Jun 17;80:100673. doi: 10.1016/j.clinsp.2025.100673.

Abstract

PURPOSE

Alzheimer's disease is a debilitating neurological disorder that requires accurate diagnosis for the most effective therapy and care.

METHODS

This article presents a new vision transformer model specifically created to evaluate magnetic resonance imaging data from the Alzheimer's Disease Neuroimaging Initiative dataset in order to categorize cases of Alzheimer's disease. Contrary to models that rely on convolutional neural networks, the vision transformer has the ability to capture large relationships between far-apart pixels in the images. The suggested architecture has shown exceptional outcomes, as its precision has emphasized its capacity to detect and distinguish significant characteristics from MRI scans, hence enabling the precise classification of Alzheimer's disease subtypes and various stages. The model utilizes both the elements from convolutional neural network and vision transformer models to extract both local and global visual patterns, facilitating the accurate categorization of various Alzheimer's disease classifications. We specifically focus on the term 'dementia in patients with Alzheimer's disease' to describe individuals who have progressed to the dementia stage as a result of AD, distinguishing them from those in earlier stages of the disease.

RESULTS

Precise categorization of Alzheimer's disease has significant therapeutic importance, as it enables timely identification, tailored treatment strategies, disease monitoring, and prognostic assessment.

CONCLUSION

The stated high accuracy indicates that the suggested vision transformer model has the capacity to assist healthcare providers and researchers in generating well-informed and precise evaluations of individuals with Alzheimer's disease.

摘要

目的

阿尔茨海默病是一种使人衰弱的神经疾病,需要准确诊断以实现最有效的治疗和护理。

方法

本文提出了一种新的视觉Transformer模型,该模型专门用于评估来自阿尔茨海默病神经影像倡议数据集的磁共振成像数据,以便对阿尔茨海默病病例进行分类。与依赖卷积神经网络的模型不同,视觉Transformer能够捕捉图像中远距离像素之间的大关系。所建议的架构已显示出卓越的成果,因为其精度突出了其从MRI扫描中检测和区分显著特征的能力,从而能够对阿尔茨海默病亚型和不同阶段进行精确分类。该模型利用卷积神经网络和视觉Transformer模型的元素来提取局部和全局视觉模式,有助于对各种阿尔茨海默病分类进行准确分类。我们特别关注“阿尔茨海默病患者的痴呆症”这一术语,以描述那些因阿尔茨海默病而进展到痴呆阶段的个体,将他们与疾病早期阶段的个体区分开来。

结果

阿尔茨海默病的精确分类具有重要的治疗意义,因为它能够实现及时识别、量身定制的治疗策略、疾病监测和预后评估。

结论

所述的高精度表明,所建议的视觉Transformer模型有能力协助医疗保健提供者和研究人员对阿尔茨海默病患者进行明智且精确的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a87/12212162/0fbdd2506a36/gr1.jpg

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