Ghattas Souad, El Bitar Jad, Maalouf Hani, El Asmar Antoine, El Rassi Ziad, Dib Wissam
Department of General Surgery - Balamand University -Saint Georges Hospital University Medical Center, Beirut, Lebanon.
Department of General Surgery - Balamand University -Saint Georges Hospital University Medical Center, Beirut, Lebanon.
Int J Surg Case Rep. 2025 Jun 13;133:111505. doi: 10.1016/j.ijscr.2025.111505.
Anal metastasis from colorectal cancer is extremely rare, since most cases in the literature are associated with a history of anal disease, such as anal fistula, fissure, hemorrhoidectomy, and anastomotic injury.
Herein, we report the case of a 63-year-old male patient, who presented with synchronous anal metastasis from a sigmoid cancer in the absence of epithelial damage treated with trimodality therapy that consisted of neoadjuvant chemoradiotherapy followed by abdominoperineal resection.
True cutaneous metastases to the anal skin from colonic carcinomas are exceedingly uncommon and are likely underpinned by diverse mechanisms such as lymphatic dissemination, transperitoneal extension, direct extension, retrograde vascular dissemination, or systemic hematogenous spread. This pattern of metastasis is particularly observed in advanced tumor presentations.
This report guides clinicians to think about this rare type of metastasis. However, more clinical data is necessary to establish treatment and postoperative management plan for anal metastasis derived from colorectal cancer.
结直肠癌的肛门转移极为罕见，因为文献中的大多数病例都与肛门疾病史有关，如肛瘘、肛裂、痔切除术和吻合口损伤。
在此，我们报告一例63岁男性患者，其患有乙状结肠癌同步肛门转移，在没有上皮损伤的情况下接受了新辅助放化疗后行腹会阴联合切除术的三联疗法。
结肠癌真正转移至肛门皮肤极为罕见，可能由多种机制导致，如淋巴扩散、经腹膜延伸、直接蔓延、逆行血管扩散或全身血行播散。这种转移模式在晚期肿瘤表现中尤为常见。
本报告引导临床医生考虑这种罕见的转移类型。然而，需要更多临床数据来制定结直肠癌肛门转移的治疗和术后管理方案。
