Hecquet B, Vennin P, Fournier C, Lefebvre J L, Caty A, Bonneterre J, Adenis L, Demaille A
Cancer Chemother Pharmacol. 1985;15(3):310-2. doi: 10.1007/BF00263908.
Intratumoral platinum concentrations were measured in three tumor sites (head and neck, uterine cervix, and breast) 48 h after cisplatin administration according to the same protocol. The platinum levels were in the same order of magnitude in all tumors, but the concentration in breast tumors was found to be higher than that in tumors of the head and neck and of the uterine cervix.
按照相同方案,在顺铂给药48小时后,测量了三个肿瘤部位(头颈部、子宫颈和乳腺)的瘤内铂浓度。所有肿瘤中的铂水平处于相同数量级,但发现乳腺肿瘤中的浓度高于头颈部肿瘤和子宫颈肿瘤中的浓度。