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顺铂治疗后人类头颈部、子宫颈和乳腺肿瘤中的铂浓度。

Platinum concentration in human tumors of head and neck, uterine cervix, and breast following treatment with cisplatin.

作者信息

Hecquet B, Vennin P, Fournier C, Lefebvre J L, Caty A, Bonneterre J, Adenis L, Demaille A

出版信息

Cancer Chemother Pharmacol. 1985;15(3):310-2. doi: 10.1007/BF00263908.

DOI:10.1007/BF00263908
PMID:4053273
Abstract

Intratumoral platinum concentrations were measured in three tumor sites (head and neck, uterine cervix, and breast) 48 h after cisplatin administration according to the same protocol. The platinum levels were in the same order of magnitude in all tumors, but the concentration in breast tumors was found to be higher than that in tumors of the head and neck and of the uterine cervix.

摘要

按照相同方案，在顺铂给药48小时后，测量了三个肿瘤部位（头颈部、子宫颈和乳腺）的瘤内铂浓度。所有肿瘤中的铂水平处于相同数量级，但发现乳腺肿瘤中的浓度高于头颈部肿瘤和子宫颈肿瘤中的浓度。

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1
Platinum concentration in human tumors of head and neck, uterine cervix, and breast following treatment with cisplatin.顺铂治疗后人类头颈部、子宫颈和乳腺肿瘤中的铂浓度。
Cancer Chemother Pharmacol. 1985;15(3):310-2. doi: 10.1007/BF00263908.
2
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Anticancer Res. 1985 Jul-Aug;5(4):369-70.
3
Tumor concentration of platinum in patients with head and neck cancer.
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Comparison of platinum concentrations in human head and neck tumours following administration of carboplatin, iproplatin or cisplatin.卡铂、异丙铂或顺铂给药后人体头颈部肿瘤中铂浓度的比较。
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5
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本文引用的文献

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Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs.给狗静脉注射顺二氯二氨铂（II）（NSC 119875）后铂的分布与处置情况。
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