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乳腺超声检查的主要发现——导管异常:文献综述及分类建议

Ductal abnormalities as primary findings on breast ultrasonography: a literature review and proposed classification.

作者信息

Oba Ken, Tsunoda Hiroko, Moon Woo Kyung

机构信息

Department of Radiology, St. Luke's International Hospital, Tokyo, Japan.

Department of Radiology, Seoul National University Hospital, Seoul, Korea.

出版信息

Ultrasonography. 2025 Jul;44(4):245-259. doi: 10.14366/usg.25048. Epub 2025 May 6.

DOI:10.14366/usg.25048
PMID:40534164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12242359/
Abstract

Ductal abnormalities, such as dilated ducts with intraductal lesions, are frequently the primary ultrasound findings prompting biopsy and resulting in the early diagnosis of breast cancer or high-risk lesions. However, the Breast Imaging Reporting and Data System (BI-RADS) ultrasound lexicon provides limited guidance on these findings, categorizing them merely as associated features. To address this limitation, this review presents a critical analysis of existing literature and proposes a new classification encompassing three distinct subtypes: dilated ducts alone, dilated ducts with intraductal echoes, and intraductal masses. Additionally, an interpretation algorithm is introduced that incorporates lesion size and suspicious ultrasound features to guide BI-RADS assessment. This structured approach aims to standardize terminology, improve diagnostic accuracy, and promote consistent management of ductal abnormalities, especially in asymptomatic women.

摘要

导管异常,如伴有导管内病变的扩张导管,常常是促使进行活检并导致乳腺癌或高危病变早期诊断的主要超声检查结果。然而,乳腺影像报告和数据系统(BI-RADS)超声术语对这些发现的指导有限,仅将它们归类为相关特征。为解决这一局限性,本综述对现有文献进行了批判性分析,并提出了一种新的分类方法,包括三个不同的亚型:单纯扩张导管、伴有导管内回声的扩张导管和导管内肿块。此外,还引入了一种解读算法,该算法纳入病变大小和可疑超声特征以指导BI-RADS评估。这种结构化方法旨在规范术语,提高诊断准确性,并促进对导管异常的一致管理, 尤其是在无症状女性中。

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本文引用的文献

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Radiology. 2024 Nov;313(2):e240043. doi: 10.1148/radiol.240043.
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Usefulness of color Doppler and strain elastography adjunctive to B-mode ultrasonography in the diagnosis of non-mass abnormalities of the breast: results of the BC-07 multicenter study of 385 cases.B超联合彩色多普勒及应变弹性成像在乳腺非肿块性病变诊断中的应用价值:BC-07多中心385例研究结果
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ESR Essentials: diagnostic work-up in patients with symptomatic breast disease-practice recommendations by the European Society of Breast Imaging.
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Eur Radiol. 2025 Feb;35(2):723-732. doi: 10.1007/s00330-024-10980-5. Epub 2024 Jul 31.
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Charged with Discharge: A Case-based Review of Nipple Discharge Using the American College of Radiology's Appropriateness Guidelines.带电荷与放电:基于病例对乳头溢液的回顾,采用美国放射学会的适宜性指南
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Malignant upgrade rate and associated clinicopathologic predictors for concordant intraductal papilloma without atypia: A systematic review and meta-analysis.一致性无非典型性导管内乳头状瘤的恶性升级率及其相关临床病理预测因素:系统评价和荟萃分析。
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Overcoming the limitations of screening mammography in Japan and Korea: a paradigm shift to personalized breast cancer screening based on ultrasonography.克服日本和韩国乳腺钼靶筛查的局限性:向基于超声的个性化乳腺癌筛查的范式转变。
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