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《用于国际疾病分类第11版(ICD-11)和精神疾病诊断与统计手册第5版修订版(DSM-5-TR)中持续性悲伤障碍的奥胡斯结构化临床访谈(A-PGDi)的开发与验证》

Development and validation of the Aarhus Structured Clinical Interview for Prolonged Grief Disorder in ICD-11 and DSM-5-TR (A-PGDi).

作者信息

O'Connor Maja, Vang Maria Louison, Bryant Richard A, Buur Christina, Komischke-Konnerup Katrine B, Frostholm Lisbeth, Ladegaard Nicolai

机构信息

Unit for Bereavement Research, Department of Psychology, Aarhus University, Aarhus, Denmark.

The Danish National Center for Grief, Copenhagen, Denmark.

出版信息

Eur J Psychotraumatol. 2025 Dec;16(1):2511373. doi: 10.1080/20008066.2025.2511373. Epub 2025 Jun 19.

DOI:10.1080/20008066.2025.2511373
PMID:40534423
Abstract

Prolonged Grief Disorder (PGD) is a new disorder. A structured clinical interview for ICD-11 and DSM-5-TR PGD is a necessary tool in diagnosing PGD needed as PGD is implemented as a mental disorder in health services across the world. This study developed and validated The Aarhus PGD Interview (A-PGDi) to provide clinicians with free access to a valid method to diagnose PGD in alignment with recent diagnostic requirements in ICD-11 and DSM-5-TR and to training materials. The A-PGDi was developed in close collaboration between scientists, clinicians, and bereaved individuals. First, all PGD-symptoms underwent two rounds of item-formulations by clinicians and researchers. Then, a first version of the A-PGDi was tested in a group of bereaved adults with PGD symptoms, who were interviewed about the A-PGDi. The A-PGDi was refined according to their responses, piloted in 13 bereaved adults and further refined to its final version. The validity of A-PGDi was then tested with clinical interviews for PGD, PTSD, depression, and anxiety performed by carefully trained clinical interviewers in a sample of 124 bereaved adults (mean age 47 years (range 19-83 years); 85% female). Benchmarked against a self-report measure of PGD and moderate to substantial inter-diagnostic agreement between ICD-11 and DSM-5-TR diagnoses the A-PGDi had sufficient content validity. Significant relations between PGD-diagnosis and other mental disorders estimated with clinical interviews and self-report scales and moderate to substantial inter-diagnostic and test-retest agreement indicated sufficient criterion validity and reliability. small non-probability sample with PGD symptoms; self-identified for participation; mostly female. The results indicate that A-PGDi with some limitations is a valid structured clinical interview for diagnosing both ICD-11 and DSM-5-TR PGD that is relevant to administer in mental health settings to ensure correct diagnostics and the most helpful treatment plan for people with PGD.

摘要

持续性悲伤障碍(PGD)是一种新的疾病。针对国际疾病分类第11版(ICD - 11)和精神疾病诊断与统计手册第5版修订版(DSM - 5 - TR)的PGD进行的结构化临床访谈,是诊断PGD的必要工具,因为PGD在全球卫生服务中被列为一种精神障碍。本研究开发并验证了奥胡斯PGD访谈(A - PGDi),为临床医生提供一种有效的方法,以便根据ICD - 11和DSM - 5 - TR的最新诊断要求诊断PGD,并提供培训材料。A - PGDi是在科学家、临床医生和丧亲者的密切合作下开发的。首先,临床医生和研究人员对所有PGD症状进行了两轮项目制定。然后,A - PGDi的第一版在一组有PGD症状的丧亲成年人中进行了测试,这些人接受了关于A - PGDi的访谈。A - PGDi根据他们的回答进行了完善,在13名丧亲成年人中进行了试点,并进一步完善为最终版本。然后,由经过精心培训的临床访谈者在124名丧亲成年人(平均年龄47岁(范围19 - 83岁);85%为女性)的样本中,通过对PGD、创伤后应激障碍(PTSD)(创伤后应激障碍)、抑郁症和焦虑症的临床访谈来测试A - PGDi的有效性。以PGD的自我报告测量为基准,以及ICD - 11和DSM - 5 - TR诊断之间中度到高度的诊断间一致性,A - PGDi具有足够的内容效度。通过临床访谈和自我报告量表估计的PGD诊断与其他精神障碍之间的显著关系,以及中度到高度的诊断间和重测一致性表明具有足够的标准效度和信度。样本为有PGD症状的小概率非样本;自我确定参与;大多为女性。结果表明,A - PGDi虽有一些局限性,但仍是一种有效的结构化临床访谈,可用于诊断ICD - 11和DSM - 5 - TR的PGD,在心理健康环境中进行管理以确保正确诊断,并为患有PGD的人制定最有效的治疗计划。

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