玻璃体切割术期间角膜基质透镜移植覆盖黄斑裂孔
Corneal stromal lenticule transplantation for covering macular hole during vitrectomy.
作者信息
Ding Wen-Ting, Xu Yi-Le, Li Di, Qian Xiao-Xiao, Li Jian, Ge Hong-Wei, Zhang Xiao-Hua, Hu Ren-Jian, Hu Yong-Ping
机构信息
Department of Ophthalmology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China.
Department of Urology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China.
出版信息
Int J Ophthalmol. 2025 Jun 18;18(6):1163-1168. doi: 10.18240/ijo.2025.06.24. eCollection 2025.
AIM
To describe an innovative surgical technique for pathologic myopia and macular holes accompanied by retinal detachment using allogeneic corneal stromal lenticule transplantation combined with pars plana vitrectomy.
METHODS
The allogeneic corneal stromal lenticule was harvested through small incision lenticule extraction (SMILE) and stored at -30°C in advance. After pars plana vitrectomy, an allogeneic corneal stromal lenticule was thawed, trimmed into approximately 60 µm thick and 100 µm larger than the macular hole and transferred to cover the macular hole through the trocar. Autologous whole blood was dripped to seal the corneal stromal lenticule. The vitreous cavity was then filled with perfluoropropane (CF) or sterile air.
RESULTS
The technique was performed on three eyes of three patients. The mean postoperative follow-up period was 77.3±50.0d. Postoperatively, the macular hole of all eyes was restored. All patients' visual acuities also improved. No complications occurred during the follow-up period.
CONCLUSION
The innovative corneal stromal lenticule transplantation technique provides convenient operations, less surgical invasion, effective results, and reliable safety for macular hole repair during follow-up time.
目的
描述一种采用同种异体角膜基质透镜移植联合玻璃体切除术治疗病理性近视合并黄斑裂孔伴视网膜脱离的创新手术技术。
方法
通过小切口透镜切除术（SMILE）获取同种异体角膜基质透镜，并预先储存在-30°C。在玻璃体切除术后，将同种异体角膜基质透镜解冻，修剪成约60μm厚且比黄斑裂孔大100μm，通过套管针转移至黄斑裂孔处覆盖。滴注自体全血以封闭角膜基质透镜。然后玻璃体腔内填充全氟丙烷（CF）或无菌空气。
结果
该技术应用于3例患者的3只眼。术后平均随访时间为77.3±50.0天。术后，所有眼的黄斑裂孔均修复。所有患者的视力也得到改善。随访期间未发生并发症。
结论
创新的角膜基质透镜移植技术为随访期间黄斑裂孔修复提供了操作简便、手术侵袭性小、效果确切及安全性可靠的优势。
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