Chen Xiao-Na, Xiong Ying-Yue, Wei Jia, Luo Bin, Gao Ya-Li
Jinan University, Guangzhou 510632, Guangdong Province, China.
Department of Ophthalmology, Shenzhen People's Hospital (the Second Clinical Medical College, Jinan University), Shenzhen 518020, Guangdong Province, China.
Int J Ophthalmol. 2025 Jun 18;18(6):1023-1031. doi: 10.18240/ijo.2025.06.08. eCollection 2025.
To explore the effect of Alpha angle and Kappa angle before multifocal intraocular lenses (MIOLs) implantation on postoperative visual quality of patients.
Before and 3mo after cataract surgery, Alpha angle and Kappa angle were collected using IOL Master 700, iTrace, and Pentacam for clinical observation. Postoperative visual quality indicators, including high-order aberrations (HOA), modulation transfer function (MTF) and point spread function (PSF), were collected using iTrace. multiple linear regression analysis was used to analyze the correlation of the Kappa angle and the Alpha angle with age, axial length (AL), anterior chamber depth (ACD), keratometry (K), lens thickness (LT) and corneal white to white distance (WTW). Pearson correlation coefficient was used to analyze the correlation between Alpha angle and Kappa angle; Bland Altman analysis was used to evaluate the consistency of pairwise detection results of three instruments.
The Alpha angle was modeled as Alpha=2.230+0.003×age-0.036×AL-0.025×K-0.058×WTW and the Kappa angle was modeled as Kappa=0.685+ 0.003×age-0.013×K-0.061×WTW. The correlation between the total Alpha angle and Kappa angle of the three instruments was weakly positive (=0.291, =0.000). Comparing the measurement of Alpha angle and Kappa angle using three instruments, only IOL Master 700 and iTrace showed good consistency in measuring Kappa angle (=0.4254). After 3mo of surgery, the Alpha angle and Kappa angle significantly decreased (=0.011, 0.018; =0.008, 0.036). △Kappa=1.136-0.021×AL-0.013×K. Kappa angle could positively predict HOA (=0.18, =0.000), MTF (=0.171, =0.000), PSF (=0.088, =0.000), Alpha angle cannot (>0.05).
The patients with older age, flatter K and shorter WTW should be alert to the possibility of larger Alpha angle and Kappa angle. Alpha angle should also consider the factor of AL. When selecting patients with MIOLs implantation, there is no need to consider the Alpha angle. Careful consideration should be given to the Kappa angle, and the preoperative standard of <0.5 mm can refer to △Kappa=1.136-0.021×AL-0.013×K and be appropriately relaxed.
探讨多焦点人工晶状体(MIOLs)植入术前α角和κ角对患者术后视觉质量的影响。
在白内障手术前及术后3个月,使用IOL Master 700、iTrace和Pentacam收集α角和κ角进行临床观察。使用iTrace收集术后视觉质量指标,包括高阶像差(HOA)、调制传递函数(MTF)和点扩散函数(PSF)。采用多元线性回归分析分析κ角和α角与年龄、眼轴长度(AL)、前房深度(ACD)、角膜曲率(K)、晶状体厚度(LT)和角膜白对白距离(WTW)的相关性。采用Pearson相关系数分析α角与κ角之间的相关性;采用Bland Altman分析评估三种仪器两两检测结果的一致性。
α角的模型为α = 2.230 + 0.003×年龄 - 0.036×AL - 0.025×K - 0.058×WTW,κ角的模型为κ = 0.685 + 0.003×年龄 - 0.013×K - 0.061×WTW。三种仪器总的α角与κ角之间的相关性呈弱正相关(r = 0.291,P = 0.000)。比较三种仪器测量α角和κ角的结果,仅IOL Master 700和iTrace在测量κ角方面显示出良好的一致性(r = 0.4254)。手术后3个月,α角和κ角显著减小(P = 0.011,0.018;P = 0.008,0.036)。△κ = 1.136 - 0.021×AL - 0.013×K。κ角可正向预测HOA(r = 0.18,P = 0.000)、MTF(r = 0.171,P = 0.000)、PSF(r = 0.088,P = 0.000),α角则不能(P>0.05)。
年龄较大、角膜曲率较平、WTW较短的患者应警惕α角和κ角较大的可能性。α角还应考虑AL因素。在选择植入MIOLs的患者时,无需考虑α角。应仔细考虑κ角,术前<0.5 mm的标准可参考△κ = 1.136 - 0.021×AL - 0.013×K并适当放宽。