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在退伍军人事务部体外膜肺氧合(VA ECMO)中重新定义撤机:泵控逆行撤离试验的病例报告

Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off.

作者信息

Deshpande Raghavendra, Rangappa Rajavardhan, Kanjilal Saikat, Moola Narayana Swamy, Kumar Suriyanathan Madhan

机构信息

Department of Critical Care, Manipal Hospital Sarjapur Road, Bengaluru, 560102 India.

Department of Cardiology, Manipal Hospital Sarjapur Road, Bengaluru, 560102 India.

出版信息

Indian J Thorac Cardiovasc Surg. 2025 Jul;41(7):937-941. doi: 10.1007/s12055-025-01895-x. Epub 2025 Feb 1.

DOI:10.1007/s12055-025-01895-x
PMID:40535211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12170960/
Abstract

UNLABELLED

Extracorporeal membrane oxygenation (ECMO) is widely recognized as a life-saving measure. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is on the rise, serving as an effective mechanical circulatory support (MCS) device that aids in the restoration of systemic perfusion in patients suffering from cardiogenic shock. Weaning methods for VA ECMO exhibit considerable variability, with pump-controlled retrograde trial off (PCRTO) being one of the methods employed. PCRTO is a practical weaning method due to its physiological approach. In this case report, we discuss the application of PCRTO, in conjunction with a pulmonary artery catheter, for weaning a 41-year-old male patient from VA ECMO. The patient presented with acute coronary syndrome with cardiogenic shock. PCRTO played a pivotal role in the successful explantation of the ECMO cannulae, particularly given the patient's uncertain cardiorespiratory recovery. The PCRTO method, being both feasible and reversible, serves as a significant predictor for successful weaning from VA ECMO through a preload stress test. This case underscores the potential of PCRTO as a valuable tool in the weaning process from VA ECMO.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12055-025-01895-x.

摘要

未标注

体外膜肺氧合(ECMO)被广泛认为是一种挽救生命的措施。静脉-动脉体外膜肺氧合(VA ECMO)的使用正在增加,它作为一种有效的机械循环支持(MCS)设备,有助于恢复心源性休克患者的全身灌注。VA ECMO的撤机方法存在很大差异,泵控逆行试验撤机(PCRTO)是其中一种使用的方法。由于其生理方法,PCRTO是一种实用的撤机方法。在本病例报告中,我们讨论了结合肺动脉导管使用PCRTO为一名41岁男性患者撤离VA ECMO的情况。该患者表现为急性冠状动脉综合征并伴有心源性休克。PCRTO在成功拔除ECMO插管中起了关键作用,特别是考虑到患者心肺恢复情况不确定。PCRTO方法既可行又可逆,通过预负荷压力测试可作为从VA ECMO成功撤机的重要预测指标。本病例强调了PCRTO作为VA ECMO撤机过程中有价值工具的潜力。

补充信息

在线版本包含可在10.1007/s12055-025-01895-x获取的补充材料。

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本文引用的文献

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Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis.肺动脉压和静脉动脉体外膜肺氧合期间的死亡率:ELSO 登记分析。
Circ Heart Fail. 2024 Jul;17(7):e011123. doi: 10.1161/CIRCHEARTFAILURE.123.011123. Epub 2024 Jul 9.
2
Early experience of pump-controlled retrograde trial off for weaning from veno-arterial extracorporeal membrane oxygenation in adult patients with cardiogenic shock.泵控逆行试验脱机用于心源性休克成年患者静脉-动脉体外膜肺氧合撤机的早期经验。
Perfusion. 2021 May;36(4):401-406. doi: 10.1177/0267659120941328. Epub 2020 Aug 13.
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Update on Weaning from Veno-Arterial Extracorporeal Membrane Oxygenation.静脉-动脉体外膜肺氧合撤机的最新进展
J Clin Med. 2020 Apr 2;9(4):992. doi: 10.3390/jcm9040992.
4
ECMO and Right Ventricular Failure: Review of the Literature.体外膜肺氧合与右心衰竭:文献复习。
J Intensive Care Med. 2021 Mar;36(3):352-360. doi: 10.1177/0885066619900503. Epub 2020 Jan 22.
5
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6
The ICM research agenda on extracorporeal life support.国际体外生命支持组织的研究议程。
Intensive Care Med. 2017 Sep;43(9):1306-1318. doi: 10.1007/s00134-017-4803-3. Epub 2017 May 3.
7
Right-left ventricular interdependence: a promising predictor of successful extracorporeal membrane oxygenation (ECMO) weaning after assistance for refractory cardiogenic shock.左右心室相互依存:难治性心源性休克辅助治疗后成功撤离体外膜肺氧合(ECMO)的一个有前景的预测指标。
Intensive Care Med. 2017 Apr;43(4):592-594. doi: 10.1007/s00134-016-4657-0. Epub 2016 Dec 23.
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