• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脊髓刺激治疗腹部弥漫性内脏痛觉过敏:一例报告及文献综述

Spinal Cord Stimulation for Diffuse Visceral Hyperalgesia in the Abdomen: A Case Report and Literature Review.

作者信息

Mamaril-Davis James, Palsma Ryan, Weinand Martin

机构信息

College of Medicine, The University of Arizona College of Medicine - Tucson, Tucson, AZ, USA.

Department of Neurosurgery, Banner University Medical Center/University of Arizona, Tucson, AZ, USA.

出版信息

Case Rep Gastroenterol. 2025 Jun 18;19(1):461-466. doi: 10.1159/000546229. eCollection 2025 Jan-Dec.

DOI:10.1159/000546229
PMID:40535309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12176363/
Abstract

INTRODUCTION

Spinal cord stimulation (SCS) for chronic abdominal pain is not novel. However, this has been explored only when the pain has a clear dermatomal association such as the right upper quadrant for sphincter of Oddi dysfunction or the left upper quadrant for post-traumatic splenectomy. The present report thereby discusses the utility of SCS when the visceral pain is diffusely distributed across all four quadrants of the abdomen.

CASE PRESENTATION

A patient in their 70s presented with a 30-year history of chronic abdominal pain diffusely located in all four quadrants. The patient had a pancreatic cyst removed via pancreaticoduodenectomy in 1991 complicated by chronic pancreatitis and visceral hyperalgesia. After failed pharmacological management and various outpatient nerve blocks and trigger point injections, the patient underwent SCS placement via five 4-contact paddle leads at the mid- to superior thoracic 7 level. At 1-month follow-up, the patient's visual analog scale score decreased from 8/10 (prior to implantation) to 0/10. The patient also discontinued his chronic opioid regimen post-SCS placement but continued duloxetine. Device settings remained the same throughout the postoperative period: pulse width of 500 microseconds (inter-burst) and 1,000 microseconds, frequency of 40 Hertz, and current of 1.7 milliamperes. At 12-month follow-up, the patient continued to report >90% pain relief at nearly the same SCS settings as the initial programming.

CONCLUSION

SCS may be a reliable treatment option for chronic abdominal, visceral hyperalgesia when the pain is diffusely located in all 4 quadrants and without a clear dermatomal pattern.

摘要

引言

脊髓刺激(SCS)用于慢性腹痛并非新鲜事物。然而,仅在疼痛具有明确的皮节关联时才进行探索,例如Oddi括约肌功能障碍的右上腹或创伤后脾切除术的左上腹。本报告因此讨论了在内脏疼痛广泛分布于腹部所有四个象限的情况下SCS的效用。

病例介绍

一名70多岁的患者,有30年慢性腹痛病史,疼痛广泛分布于所有四个象限。该患者于1991年接受了胰十二指肠切除术以切除胰腺囊肿,术后并发慢性胰腺炎和内脏痛觉过敏。在药物治疗失败以及各种门诊神经阻滞和触发点注射均无效后,患者于胸7中上部水平通过五条4触点片状电极导线进行了SCS植入。在1个月的随访中,患者的视觉模拟评分从植入前的8/10降至0/10。患者在SCS植入后也停用了慢性阿片类药物治疗方案,但继续服用度洛西汀。术后整个期间设备设置保持不变:脉冲宽度为500微秒(脉冲间期)和1000微秒,频率为40赫兹,电流为1.7毫安。在12个月的随访中,患者继续报告在与初始编程几乎相同的SCS设置下疼痛缓解>90%。

结论

当疼痛广泛分布于所有四个象限且无明确皮节模式时,SCS可能是慢性腹部内脏痛觉过敏的可靠治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/12176363/4a227ff1de21/crg-2025-0019-0001-546229_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/12176363/4a227ff1de21/crg-2025-0019-0001-546229_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/12176363/4a227ff1de21/crg-2025-0019-0001-546229_F01.jpg

相似文献

1
Spinal Cord Stimulation for Diffuse Visceral Hyperalgesia in the Abdomen: A Case Report and Literature Review.脊髓刺激治疗腹部弥漫性内脏痛觉过敏:一例报告及文献综述
Case Rep Gastroenterol. 2025 Jun 18;19(1):461-466. doi: 10.1159/000546229. eCollection 2025 Jan-Dec.
2
How Does Anterior Vertebral Body Tethering Compare to Posterior Spinal Fusion for Thoracic Idiopathic Scoliosis? A Nonrandomized Clinical Trial.对于青少年特发性脊柱侧凸,椎体前路栓系术与后路脊柱融合术相比效果如何?一项非随机临床试验。
Clin Orthop Relat Res. 2025 Jun 19. doi: 10.1097/CORR.0000000000003575.
3
Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis.抗血管内皮生长因子药物与激光光凝术治疗增殖性糖尿病视网膜病变的比较:一项系统评价和个体参与者数据荟萃分析
Health Technol Assess. 2025 Apr 2:1-75. doi: 10.3310/MJYP6578.
4
Aural toilet (ear cleaning) for chronic suppurative otitis media.慢性化脓性中耳炎的耳道清理(耳部清洁)
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013057. doi: 10.1002/14651858.CD013057.pub3.
5
Indications for percutaneous and paddle leads for patients with chronic spinal pain: a systematic review.慢性脊柱疼痛患者经皮和板状电极导线的适应症:一项系统评价
Reg Anesth Pain Med. 2025 Jun 19. doi: 10.1136/rapm-2025-106686.
6
Regional analgesia techniques for postoperative pain after breast cancer surgery: a network meta-analysis.乳腺癌手术后疼痛的区域镇痛技术:一项网状Meta分析
Cochrane Database Syst Rev. 2025 Jun 4;6(6):CD014818. doi: 10.1002/14651858.CD014818.pub2.
7
Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis.抗血管内皮生长因子药物与激光光凝术治疗糖尿病性视网膜病变的比较:一项系统评价和荟萃分析。
Health Technol Assess. 2024 Dec 11:1-71. doi: 10.3310/PCGV5709.
8
Transversus abdominis plane (TAP) blocks for prevention of postoperative pain in women undergoing laparoscopic and robotic gynaecological surgery.腹横肌平面(TAP)阻滞预防腹腔镜及机器人辅助妇科手术女性患者术后疼痛
Cochrane Database Syst Rev. 2025 Apr 3;4(4):CD015145. doi: 10.1002/14651858.CD015145.pub2.
9
Hospital Volume and Social Determinants of Health Do Not Impact Outcomes in Fenestrated Visceral Segment Endovascular Aortic Repair for Patients Treated at VQI Centers.医院手术量和健康的社会决定因素对在VQI中心接受治疗的患者进行开窗内脏段血管腔内主动脉修复术的预后没有影响。
Vasc Endovascular Surg. 2025 Aug;59(6):584-593. doi: 10.1177/15385744251330017. Epub 2025 Mar 24.
10
Cost-utility Analysis of Evoke Closed-loop Spinal Cord Stimulation for Chronic Back and Leg Pain.诱发闭环脊髓刺激治疗慢性腰背和下肢疼痛的成本-效用分析
Clin J Pain. 2023 Oct 1;39(10):551-559. doi: 10.1097/AJP.0000000000001146.

本文引用的文献

1
Spinal Cord Stimulation for Intractable Visceral Pain Originating from the Pelvic and Abdominal Region: A Narrative Review on a Possible New Indication for Patients with Therapy-Resistant Pain.脊髓刺激治疗源于盆腔和腹部区域的顽固性内脏疼痛:对难治性疼痛患者一种可能新适应症的叙述性综述
J Pain Res. 2024 Feb 19;17:691-736. doi: 10.2147/JPR.S445616. eCollection 2024.
2
Complications of Spinal Cord Stimulators-A Comprehensive Review Article.脊髓刺激器并发症——一篇全面的综述文章。
Curr Pain Headache Rep. 2024 Jan;28(1):1-9. doi: 10.1007/s11916-023-01178-3. Epub 2023 Oct 19.
3
Spinal cord stimulation for genitofemoral neuropathy: A case report and review of the literature.
脊髓刺激治疗生殖股神经病变:一例病例报告及文献综述
Surg Neurol Int. 2022 Nov 18;13:533. doi: 10.25259/SNI_901_2022. eCollection 2022.
4
Visceral versus somatic pain: an educational review of anatomy and clinical implications.内脏痛与躯体痛:解剖学教学综述及其临床意义。
Reg Anesth Pain Med. 2021 Jul;46(7):629-636. doi: 10.1136/rapm-2020-102084.
5
Gastrointestinal pain.胃肠道疼痛。
Nat Rev Dis Primers. 2020 Jan 6;6(1):1. doi: 10.1038/s41572-019-0135-7.
6
Visceral Pain.内脏痛。
Annu Rev Physiol. 2019 Feb 10;81:261-284. doi: 10.1146/annurev-physiol-020518-114525. Epub 2018 Oct 31.
7
Physiology of Visceral Pain.内脏痛的生理学
Compr Physiol. 2016 Sep 15;6(4):1609-1633. doi: 10.1002/cphy.c150049.
8
Outcomes of percutaneous and paddle lead implantation for spinal cord stimulation: a comparative analysis of complications, reoperation rates, and health-care costs.脊髓刺激的经皮和板状电极植入结果:并发症、再次手术率和医疗费用的比较分析
Neuromodulation. 2013 Sep-Oct;16(5):418-26; discussion 426-7. doi: 10.1111/ner.12065. Epub 2013 May 3.
9
Percutaneous implanted paddle lead for spinal cord stimulation: technical considerations and long-term follow-up.经皮植入式桨状导联用于脊髓刺激:技术考虑因素和长期随访。
Neuromodulation. 2012 Jul;15(4):402-7. doi: 10.1111/j.1525-1403.2012.00473.x. Epub 2012 Jun 1.
10
Application of spinal cord stimulation for the treatment of abdominal visceral pain syndromes: case reports.脊髓刺激治疗内脏疼痛综合征的应用:病例报告。
Neuromodulation. 2005 Jan;8(1):14-27. doi: 10.1111/j.1094-7159.2005.05216.x.