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中国中青年急性缺血性脑卒中患者院前延误的现状及影响因素

Status and influencing factors of pre-hospital delay in young and middle-aged Chinese patients with acute ischemic stroke.

作者信息

Liu Dan, Fang Yuqi, Yin Zhuan, Zhu Qingxiang, Li Chaofeng

机构信息

Hunan Provincial Key Laboratoryof Regional Hereditary Birth Defects Prevention and Control, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, China.

Department of Emergency Medicine, Xiangya Hospital of Central South University, Changsha, China.

出版信息

Front Public Health. 2025 Jun 4;13:1539219. doi: 10.3389/fpubh.2025.1539219. eCollection 2025.

Abstract

OBJECTIVE

The purpose of this study was to investigate the status quo of prehospital delay in young and middle-aged AIS patients and analyze the main factors affecting prehospital delay in young and middle-aged AIS patients. Thus, it can provide reference for reducing prehospital delay in young and middle-aged AIS patients and promote secondary prevention of stroke.

METHODS

This cross-sectional study was conducted from May 2023 to February 2024 using convenient sampling method, and included middle-aged and young ischemic stroke patients from two top three hospitals in Hunan Province. Through questionnaire survey, social support scale, health literacy scale and medical coping style scale were used to investigate.

RESULTS

A total of 671 patients were investigated. According to the standard of 3 h from the onset of symptoms to the hospital, middle-aged and young stroke patients were divided into delayed group and non-delayed group. The results showed that 534 patients with pre-hospital delay occurred, with an incidence of 79.6%. Binary logistic regression analysis showed that the factors that extended the pre-hospital time of patients were: The onset place was at home (OR = 4.997,  = 0.011), the first symptoms were numbness and weakness of limbs (OR = 3.500,  = 0.027), avoidance coping style (OR = 1.298,  = 0.027) and submission coping style (OR = 1.721,  < 0.001). The factors that shorten the pre-hospital time of patients are: AIS was known at the time of onset (OR = 0.120,  = 0.001), the first symptoms were headache and vomiting (OR = 0.052,  < 0.001), disturbance of consciousness (OR = 0.087,  < 0.001), social support level (OR = 0.891,  = 0.001) and coping style (OR = 0.688,  < 0.001).

CONCLUSION

The incidence of pre-hospital delay in young and middle-aged ischemic stroke patients is high, and the current situation is not optimistic. Factors affecting pre-hospital delay in young and middle-aged AIS patients included location of onset, first symptoms, whether they knew that the onset was AIS, level of social support, health literacy, and coping style. In the future, these aspects can be considered to reduce the delayed development of AIS in young and middle-aged people before hospital and promote secondary prevention of stroke.

摘要

目的

本研究旨在调查中青年急性缺血性卒中(AIS)患者院前延误现状,分析影响中青年AIS患者院前延误的主要因素,为减少中青年AIS患者院前延误、促进脑卒中二级预防提供参考。

方法

本横断面研究于2023年5月至2024年2月采用方便抽样法进行,纳入湖南省两家三甲医院的中青年缺血性卒中患者。通过问卷调查,采用社会支持量表、健康素养量表和医学应对方式量表进行调查。

结果

共调查671例患者。按照症状发作至入院3小时的标准,将中青年卒中患者分为延误组和未延误组。结果显示,发生院前延误的患者有534例,发生率为79.6%。二元logistic回归分析显示,延长患者院前时间的因素有:发病地点在家(OR = 4.997,P = 0.011)、首发症状为肢体麻木无力(OR = 3.500,P = 0.027)、回避应对方式(OR = 1.298,P = 0.027)和屈服应对方式(OR = 1.721,P < 0.001)。缩短患者院前时间的因素有:发病时知晓为AIS(OR = 0.120,P = 0.001)、首发症状为头痛呕吐(OR = 0.052,P < 0.001)、意识障碍(OR = 0.087,P < 0.001)、社会支持水平(OR = 0.891,P = 0.001)和应对方式(OR = 0.688,P < 0.001)。

结论

中青年缺血性卒中患者院前延误发生率高,现状不容乐观。影响中青年AIS患者院前延误的因素包括发病地点、首发症状、是否知晓发病为AIS、社会支持水平、健康素养及应对方式。未来可从这些方面考虑减少中青年AIS患者院前延误的发生,促进脑卒中二级预防。

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