Kage Anup, Santana Yesenia C, Malcolm Ivone L, Francia Caroline, Yoong Michael, Wertheim David, Shah Divyen
Blizzard Institute, Centre for Genomics, Queen Mary University of London, London, United Kingdom.
Neonatal Intensive Care Unit, The Royal London Hospital, London, United Kingdom.
Front Pediatr. 2025 Jun 4;13:1585606. doi: 10.3389/fped.2025.1585606. eCollection 2025.
Seizures in newborn infants are considered a neurological emergency requiring prompt treatment to limit exacerbation of brain injury. Digital monitors incorporating limited channel raw EEG and amplitude-integrated EEG (aEEG/EEG) are widely used. This study aimed to determine if continuous video recording with simultaneous aEEG/EEG recording enhances seizure recognition.
Newborns at risk of seizures who underwent neuromonitoring with aEEG/EEG were prospectively recruited to an observational study in a tertiary neonatal centre. Video recordings were commenced after obtaining written consent from parents.
Simultaneous video recordings with aEEG/EEG were obtained in 15/47 newborns recruited to study. A total of 116 electrographic seizure episodes were detected on aEEG/EEG when a total of 56 episodes of abnormal movements were noted on video recordings. Only 8 of these abnormal movements had simultaneous electrographic seizures on aEEG.
Use of simultaneous video and aEEG/EEG recordings in newborns at risk of seizures is feasible. It not only assists confirmation of the presence of seizures but may also help in identifying movements associated with abnormal neurology that are not seizures.
新生儿癫痫发作被视为一种神经急症，需要及时治疗以限制脑损伤的加重。包含有限通道原始脑电图和振幅整合脑电图（aEEG/EEG）的数字监测仪被广泛使用。本研究旨在确定同步进行视频记录与aEEG/EEG记录是否能提高癫痫发作的识别率。
在一家三级新生儿中心，对有癫痫发作风险且接受aEEG/EEG神经监测的新生儿进行前瞻性观察研究。在获得家长书面同意后开始视频记录。
在纳入研究的47名新生儿中，有15名同时进行了视频记录与aEEG/EEG记录。在aEEG/EEG上共检测到116次脑电图癫痫发作，而在视频记录中总共记录到56次异常运动。其中只有8次异常运动在aEEG上同时伴有脑电图癫痫发作。
对有癫痫发作风险的新生儿同时进行视频和aEEG/EEG记录是可行的。它不仅有助于确认癫痫发作的存在，还可能有助于识别与非癫痫性异常神经功能相关的运动。
