犬肝脏和脂肪组织中的脂肪酸生物合成。

Fatty acid biosynthesis in liver and adipose tissue from dogs.

作者信息

Baldner G L, Flatt R E, Shaw R N, Beitz D C

出版信息

Comp Biochem Physiol B. 1985;82(1):153-6. doi: 10.1016/0305-0491(85)90145-2.

Abstract

Production of CO2, fatty acids and glycerol from glucose and acetate was measured in slices of liver and adipose tissue taken from mature dogs. Acetate was the predominant carbon source for de novo fatty acid synthesis in both tissues. Fatty acid synthesis occurred at greater rates in adipose tissue than in liver. Glucose provided carbon for glycerol synthesis production in adipose tissue. Results support the concept that adipose tissue, and not liver, is the principal anatomical site for fatty acid synthesis in dogs.

摘要

在取自成年犬的肝脏和脂肪组织切片中，测定了由葡萄糖和乙酸盐生成二氧化碳、脂肪酸和甘油的情况。乙酸盐是这两种组织中从头合成脂肪酸的主要碳源。脂肪组织中脂肪酸合成的速率高于肝脏。葡萄糖为脂肪组织中甘油的合成提供碳源。结果支持了这样一种观点，即犬体内脂肪酸合成的主要解剖部位是脂肪组织而非肝脏。