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草原田鼠(Microtus ochrogaster)肝脏和脂肪组织中葡萄糖、乙酸盐和乳酸盐向二氧化碳和脂肪酸的转化

Conversion of glucose, acetate and lactate to CO2 and fatty acids in liver and adipose tissue of prairie voles (Microtus ochrogaster).

作者信息

Baldner G L, Beitz D C, Hood R L

出版信息

Comp Biochem Physiol B. 1984;78(1):145-50. doi: 10.1016/0305-0491(84)90158-5.

Abstract

Production of CO2 and fatty acids from acetate, glucose and lactate was determined in slices of liver and adipose tissue from prairie voles fed either a high-starch or a high-cellulose diet. Acetate and lactate were oxidized to CO2 and converted to fatty acids at greater rates than was glucose in both liver and adipose tissue. Fatty acid synthesis occurred at greater rates in adipose tissue than in liver. Fatty acid synthesis per adipocyte increased with increased adipocyte diameter. Fiber content of diets had only minimal effect on metabolic activities of liver and adipose tissue.

摘要

在喂食高淀粉或高纤维素饮食的草原田鼠的肝脏和脂肪组织切片中,测定了乙酸盐、葡萄糖和乳酸生成二氧化碳和脂肪酸的情况。在肝脏和脂肪组织中,乙酸盐和乳酸氧化为二氧化碳并转化为脂肪酸的速率均高于葡萄糖。脂肪组织中脂肪酸合成的速率高于肝脏。每个脂肪细胞的脂肪酸合成随着脂肪细胞直径的增加而增加。饮食中的纤维含量对肝脏和脂肪组织的代谢活动影响甚微。

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