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当畸胎瘤伪装时:一例罕见的胸膜内成熟囊性畸胎瘤酷似结核性脓胸病例

When Teratoma Masquerades: A Rare Case of Intrapleural Mature Cystic Teratoma Mimicking Tuberculous Empyema.

作者信息

Abeed Nik Nuratiqah Nik, Hau Ng Boon, Sharil Nor Safiqah, Lin Andrea Ban Yu, Ezzamudin Marfua'h Nik, Haron Hairulfaizi

机构信息

Respiratory Unit, Faculty of Medicine Universiti Kebangsaan Malaysia Cheras Malaysia.

Faculty of Medicine and Health Sciences Universiti Sains Islam Antarabangsa Kuala Lumpur Malaysia.

出版信息

Respirol Case Rep. 2025 Jun 18;13(6):e70252. doi: 10.1002/rcr2.70252. eCollection 2025 Jun.

Abstract

Teratomas are germ cell tumours generally gonadal in origin and very rare, arising from extra gonadal tissue. The most common extragonadal teratomas are mediastinal, and the majority are benign. We report a case of a 49-year-old lady with recurrent right complex pleural effusion occurring a month after the completion of treatment for tuberculous empyema. Imaging from ultrasound of the thorax and contrasted enhanced computed tomography (CECT) thorax revealed multiseptated and loculated effusion in the thorax without any mediastinal and lung involvement. Surprisingly, pleural fluids were negative for tuberculosis. Despite chest drainage and initial treatment for bacterial empyema without improvement, she underwent video assisted thoracoscopy and decortication of the right pleura, and histopathological analysis revealed a mature cystic teratoma. She was discharged in good health and under yearly surveillance. The rarity of intrapleural mature cystic teratoma and its misleading presentation due to the concurrent tuberculous empyema make this case noteworthy.

摘要

畸胎瘤是一种生殖细胞肿瘤,通常起源于性腺,非常罕见,可起源于性腺外组织。最常见的性腺外畸胎瘤位于纵隔,大多数为良性。我们报告一例49岁女性,在结核性脓胸治疗结束后一个月出现复发性右侧复杂性胸腔积液。胸部超声和胸部增强计算机断层扫描(CECT)成像显示胸腔内有多房性和局限性积液,无纵隔和肺部受累。令人惊讶的是,胸腔积液结核检查为阴性。尽管进行了胸腔引流和细菌性脓胸的初始治疗但无改善,她接受了电视辅助胸腔镜检查和右侧胸膜剥脱术,组织病理学分析显示为成熟囊性畸胎瘤。她健康出院并接受年度监测。胸腔内成熟囊性畸胎瘤的罕见性及其因并发结核性脓胸而产生的误导性表现使该病例值得关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de5d/12175013/92aee056c4c3/RCR2-13-e70252-g001.jpg

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