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前交通动脉瘤手术后的遗忘综合征

Amnesic syndromes after surgery of anterior communicating artery aneurysms.

作者信息

Vilkki J

出版信息

Cortex. 1985 Sep;21(3):431-44. doi: 10.1016/s0010-9452(85)80007-1.

DOI:10.1016/s0010-9452(85)80007-1
PMID:4053628
Abstract

Five patients had severe generalized disorder of memory, which lasted for several months after anterior communicating artery aneurysm surgery. Two of them had no signs of frontal lobe lesions. They were confused for not more than four days after surgery. One of them performed normally on the non-memory tests and short-term memory tests. Cues did not substantially improve his poor memory performance. The other patient had similar test results, but he had poor imagination in an inkblot perception test. Three patients had frontal lobe lesions. Two of them were restless, confused and confabulating, with one showing apathetic and stereotyped behaviour for more than a month after surgery. On the memory tests they showed disinhibition of irrelevant associations or deficient initiative. Cueing markedly improved their poor retrieval. These defects seem to be associated with frontal lobe lesions and can affect memory but are not obligatory features of amnesia.

摘要

5例患者出现严重的广泛性记忆障碍,在前交通动脉瘤手术后持续数月。其中2例没有额叶病变的迹象。他们术后意识模糊不超过4天。其中1例在非记忆测试和短期记忆测试中表现正常。线索并未显著改善其较差的记忆表现。另1例患者有类似的测试结果,但在墨迹感知测试中想象力较差。3例患者有额叶病变。其中2例术后躁动、意识模糊且虚构,1例术后一个多月表现出淡漠和刻板行为。在记忆测试中,他们表现出无关联想的去抑制或主动性不足。线索显著改善了他们较差的回忆能力。这些缺陷似乎与额叶病变有关,可影响记忆,但并非失忆的必然特征。

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