超越断点——将抗菌药物耐药性重新概念化为地球压力的一种症状。
Beyond breakpoint - reconceptualising AMR as a symptom of planetary stress.
作者信息
Kirchhelle Claas, Roberts Adam P
机构信息
French National Institute of Health and Medical Research (INSERM), U988 CERMES3, Villejuif, France.
Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.
出版信息
NPJ Antimicrob Resist. 2025 Jun 19;3(1):57. doi: 10.1038/s44259-025-00128-w.
Abstract
Planetary boundaries range from climate change to biosphere integrity. They define the safe space for humanity. Ecosystem impacts on microbes are missing from a recent assessment showing six of nine boundaries are breached. Microbes represent enormous phylogenetic diversity and underpin multiple planetary systems. Here, we suggest that reconceiving AMR as a sign of ecosystem stress may enable us to steward our wider microbial commons, protecting planetary systems from being breached.
摘要
行星边界涵盖从气候变化到生物圈完整性等诸多方面。它们界定了人类的安全空间。最近一项评估显示九个边界中有六个已被突破，其中缺少了生态系统对微生物的影响。微生物具有巨大的系统发育多样性，并支撑着多个行星系统。在此，我们建议将抗微生物药物耐药性重新理解为生态系统压力的一种迹象，这可能使我们能够管理更广泛的微生物公共资源，保护行星系统不被突破。
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