Wenqiang Li, Zhian Chen, Hua Liu, Yang Li, Yi Cui, Zhijun Cai
Kunming Medical University, Kunming, 650500, China.
920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650032, China.
Eur J Med Res. 2025 Jun 19;30(1):495. doi: 10.1186/s40001-025-02689-y.
Spinal cord injury (SCI) is considered one of the key factors leading to severe loss of motor and sensory function, which has a profound negative impact on the quality of life of patients. With the continuous development of medical technology, neurostimulation techniques have gradually shown their importance in treating spinal cord injuries, demonstrating the potential for positive effects on functional recovery. Currently, various neurostimulation methods, including electrical stimulation, drug therapy, and biofeedback, have been employed in clinical research on spinal cord injury. Although we have achieved certain progress, there are still many unresolved mysteries regarding the performance and mechanisms of these technologies in actual clinical applications. At the same time, challenges such as individual differences and treatment efficacy evaluation also arise in clinical practice. This study aims to comprehensively review the latest research advancements in spinal cord injury neurostimulation technologies, explore their practical applications and related mechanisms in the process of functional recovery, and analyze potential future research directions, to provide innovative ideas and strategies for the treatment of spinal cord injuries.
脊髓损伤（SCI）被认为是导致运动和感觉功能严重丧失的关键因素之一，对患者的生活质量产生深远的负面影响。随着医学技术的不断发展，神经刺激技术在治疗脊髓损伤方面逐渐显示出其重要性，展现出对功能恢复产生积极影响的潜力。目前，包括电刺激、药物治疗和生物反馈在内的各种神经刺激方法已应用于脊髓损伤的临床研究。尽管我们已经取得了一定进展，但在这些技术实际临床应用中的性能和机制方面仍存在许多未解之谜。同时，临床实践中还出现了个体差异和治疗效果评估等挑战。本研究旨在全面综述脊髓损伤神经刺激技术的最新研究进展，探索其在功能恢复过程中的实际应用及相关机制，并分析未来潜在的研究方向，为脊髓损伤的治疗提供创新思路和策略。
