Guthrie Andrew, King Joshua, Casey Ashley
Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, LA.
The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.
Ochsner J. 2025 Summer;25(2):114-115. doi: 10.31486/toj.24.0103.
Carbidopa/levodopa is a vital medication administered to patients with Parkinson disease. In some clinical situations, oral administration of the medication is not feasible, so alternative routes for medication delivery must be explored to prevent severe complications.
A 90-year-old male with Parkinson disease presented from a nursing home with worsening confusion and agitation. Because of the patient's condition and the inability to obtain enteric access, carbidopa/levodopa was administered rectally, resulting in an observed reduction of the patient's Parkinson symptoms.
When patients with Parkinson disease cannot take their medications orally, rectal administration of carbidopa/levodopa may be a reasonable and effective alternative route of administration.
卡比多巴/左旋多巴是用于帕金森病患者的重要药物。在某些临床情况下，口服该药物不可行，因此必须探索其他给药途径以预防严重并发症。
一名90岁帕金森病男性患者从养老院送来，意识混乱和烦躁不安症状加重。由于患者的病情以及无法实现肠道给药，遂通过直肠给予卡比多巴/左旋多巴，结果观察到患者的帕金森症状有所减轻。
当帕金森病患者无法口服药物时，直肠给予卡比多巴/左旋多巴可能是一种合理且有效的替代给药途径。
