聚焦超声治疗宫颈人乳头瘤病毒感染及鳞状上皮内病变：一项叙述性综述
Focused ultrasound treatment of cervical human papillomavirus infection and squamous intraepithelial lesions: A narrative review.
作者信息
Cheung Vincent Y T
机构信息
Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
出版信息
Eur J Obstet Gynecol Reprod Biol X. 2025 May 28;26:100406. doi: 10.1016/j.eurox.2025.100406. eCollection 2025 Jun.
Focused ultrasound (FUS) appears to be a promising form of thermal ablation for treatment of cervical lesions, but evidence supporting its use is limited. This review evaluated the efficacy and safety of FUS treatment of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL). The overall efficacy of FUS on HPV clearance was 75.0-85.7 % at 3 months, 35.5-77.1 % at 6 months and 64.7-94.1 % at 12 months. Its efficacy on low grade SIL and high grade SIL regression were 83.3-96.8 % and 70.9-96.6 % at 6 months, respectively. Complications were uncommon. FUS appears to be an effective and safe treatment modality for cervical HPV and SIL.
聚焦超声（FUS）似乎是一种有前景的热消融治疗方法，可用于治疗宫颈病变，但支持其应用的证据有限。本综述评估了FUS治疗宫颈人乳头瘤病毒（HPV）感染和鳞状上皮内病变（SIL）的疗效和安全性。FUS清除HPV的总体疗效在3个月时为75.0 - 85.7%，6个月时为35.5 - 77.1%，12个月时为64.7 - 94.1%。其对低级别SIL和高级别SIL消退的疗效在6个月时分别为83.3 - 96.8%和70.9 - 96.6%。并发症并不常见。FUS似乎是一种治疗宫颈HPV和SIL的有效且安全的治疗方式。
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