Elhoufey Amira
Department of Community Health Nursing, Alddrab University College, Jazan University, Jazan, SAU.
Cureus. 2025 May 20;17(5):e84485. doi: 10.7759/cureus.84485. eCollection 2025 May.
This study aimed to investigate the clinical characteristics and risk factors associated with pertussis in children.
A retrospective analysis was conducted on the clinical data, risk factors, and laboratory indices of 100 children hospitalized with pertussis (pertussis group) and 100 children hospitalized with cough (control group) from January to December 2024.
The serum globulin and immunoglobulin M (IgM) levels in the pertussis group were significantly lower than those in the control group. The mean hospital stay length, C-reactive protein (CRP), and white blood cell (WBC) count were significantly higher in the pertussis group. The rates of delayed immunization and non-immunization with the diphtheria, tetanus, and pertussis (DTP) vaccine were significantly higher in the pertussis group compared to the control group.
Delayed immunization and non-immunization with the DPT vaccine were identified as risk factors for pertussis infection. Timely vaccination with the pertussis vaccine and isolation from individuals suspected of carrying the infection are crucial for reducing pertussis incidence in infants and young children.
本研究旨在调查儿童百日咳的临床特征及相关危险因素。
对2024年1月至12月期间住院的100例百日咳患儿（百日咳组）和100例咳嗽患儿（对照组）的临床资料、危险因素及实验室指标进行回顾性分析。
百日咳组血清球蛋白和免疫球蛋白M（IgM）水平显著低于对照组。百日咳组平均住院天数、C反应蛋白（CRP）及白细胞（WBC）计数显著高于对照组。百日咳组与对照组相比，白喉、破伤风和百日咳（DTP）疫苗延迟接种和未接种率显著更高。
DPT疫苗延迟接种和未接种被确定为百日咳感染的危险因素。及时接种百日咳疫苗并与疑似感染者隔离对于降低婴幼儿百日咳发病率至关重要。
