Allagbé Ingrid, Baudoin David, Rance Bastien, Le Faou Anne-Laurence
Outpatient Addictology Center, Georges Pompidou European Hospital, AP-HP, Université Paris Cité, Paris, France.
Groupement d'Intérêt Scientifique du Réseau Français d'Excellence de Recherche sur Tabac, nicotine et produits connexes (GIS REFERTab), Paris, France.
PLoS One. 2025 Jun 20;20(6):e0321764. doi: 10.1371/journal.pone.0321764. eCollection 2025.
Evidence suggests that diabetic smokers are less likely to quit smoking when compared to non-diabetic smokers. This study aimed to determine predictors of abstinence among diabetic smokers attending smoking cessation services (SCSs) across France. We analysed data from 94,827 adult smokers registered in the French national smoking cessation registry (CDTnet) between 2007 and 2016. Participants attended ≥2 SCS visits, and one-month continued abstinence was confirmed by carbon monoxide measurement. Among 6,405 diabetic smokers, 33% achieved one-month continued abstinence, versus 38% among 88,422 non-diabetic smokers (p < 0.001). Positive predictors of abstinence among diabetic smokers included employment (odds ratio [OR], 1.61; 95% confidence interval [CI], 1.37-1.89), ≥ 3 prior quit attempts (OR, 1.61; 95% CI, 1.36-1.91), low nicotine dependence (OR, 1.42; 95% CI, 1.13-1.78), prescription of combined nicotine replacement therapy (NRT) (OR, 1.43; 95% CI, 1.19-1.72) or varenicline (OR, 1.64; 95% CI, 1.20-2.25), and ≥7 SCS consultations (OR, 4.47; 95% CI, 3.40-5.84). Conversely, negative predictors included history of myocardial infarction/angina (OR, 0.82; 95% CI, 0.70-0.96), chronic bronchitis/chronic obstructive pulmonary disease (OR, 0.79; 95% CI, 0.69-0.91), anxiety (OR, 0.82; 95% CI, 0.71-0.94), recent cannabis use (OR, 0.67; 95% CI, 0.50-0.90), and exclusive oral NRT use (OR, 0.70; 95% CI, 0.56-0.88). Overall, tailored cessation programs are crucial for enhancing cessation outcomes among diabetic smokers.
有证据表明,与非糖尿病吸烟者相比,糖尿病吸烟者戒烟的可能性较小。本研究旨在确定法国各地参加戒烟服务(SCS)的糖尿病吸烟者戒断的预测因素。我们分析了2007年至2016年在法国国家戒烟登记处(CDTnet)登记的94827名成年吸烟者的数据。参与者参加了≥2次SCS访视,通过一氧化碳测量确认持续戒断一个月。在6405名糖尿病吸烟者中,33%实现了持续戒断一个月,而在88422名非糖尿病吸烟者中这一比例为38%(p<0.001)。糖尿病吸烟者戒断的积极预测因素包括就业(比值比[OR],1.61;95%置信区间[CI],1.37-1.89)、≥3次既往戒烟尝试(OR,1.61;95%CI,1.36-1.91)、低尼古丁依赖(OR,1.42;95%CI,1.13-1.78)、联合使用尼古丁替代疗法(NRT)(OR,1.43;95%CI,1.19-1.72)或伐尼克兰(OR,1.64;95%CI,1.20-2.25)以及≥7次SCS咨询(OR,4.47;95%CI,3.40-5.84)。相反,消极预测因素包括心肌梗死/心绞痛病史(OR,0.82;95%CI,0.70-0.96)、慢性支气管炎/慢性阻塞性肺疾病(OR,0.79;95%CI,0.69-0.91)、焦虑(OR,0.82;95%CI,0.71-0.94)、近期使用大麻(OR,0.67;95%CI,0.50-0.90)以及仅使用口服NRT(OR,0.70;95%CI,0.56-0.88)。总体而言,量身定制的戒烟计划对于提高糖尿病吸烟者的戒烟效果至关重要。