Cordia Q C F, Dijkstra B M, Groen R J M
Department of Neurosurgery, University Medical Centre Groningen, Hanzeplein 1, P.O. Box 30.001, Groningen, 9700RB, The Netherlands.
Department of Neurosurgery, Maastricht UMC+, Maastricht, The Netherlands.
Neurosurg Rev. 2025 Jun 21;48(1):520. doi: 10.1007/s10143-025-03658-z.
Meningiomas are the most common primary intracranial tumours. Recurrence occurs in up to 20%, with even higher percentages in atypical or malignant meningiomas. The non-removal of the dural tail may be a risk factor for recurrence. In this review, we aimed to determine the prevalence of tumour tissue in the radiological dural tail sign. Our secondary outcome was to determine the clinical relevance of the dural tail, if possible. PubMed, Embase, ISI Web of Science and the Cochrane Library were systematically searched for studies. Articles evaluating dural tails with both radiological and histopathological findings were included. Two reviewers independently screened studies. Data was extracted manually. 18 articles met the inclusion criteria out of 843 identified reports. In total, 406 patients with a radiological and histopathological evaluated dural tail were found. 286 patients (70.9%) had tumour infiltrate; 110 non-neoplastic dural tails showed vascular changes, loose connective tissue proliferation or inflammation. 65 patients with seemingly normal dura mater were reported, of which 26 (40.0%) showed tumour infiltration. It appears that tumour tissue in the radiological dural tail is common. Concerningly, approximately 40% of non-enhancing dura also revealed tumour tissue in the pathological examination. This highlights the need for further systematic research into the dural tail and its clinical impact on recurrence. Clinical trial number Not applicable.
脑膜瘤是最常见的原发性颅内肿瘤。高达20%的患者会复发，非典型或恶性脑膜瘤的复发率更高。未切除硬脑膜尾征可能是复发的危险因素。在本综述中，我们旨在确定放射学硬脑膜尾征中肿瘤组织的发生率。如果可能的话，我们的次要结果是确定硬脑膜尾征的临床相关性。我们系统检索了PubMed、Embase、ISI科学网和考科蓝图书馆中的研究。纳入评估硬脑膜尾征的放射学和组织病理学结果的文章。两名评审员独立筛选研究。数据手动提取。在843篇已识别的报告中，18篇文章符合纳入标准。总共发现406例患者的硬脑膜尾征经过了放射学和组织病理学评估。286例患者（70.9%）有肿瘤浸润；110例非肿瘤性硬脑膜尾征表现为血管改变、疏松结缔组织增生或炎症。报告了65例硬脑膜看似正常的患者，其中26例（40.0%）有肿瘤浸润。放射学硬脑膜尾征中的肿瘤组织似乎很常见。令人担忧的是，在病理检查中，约40%的无强化硬脑膜也显示有肿瘤组织。这凸显了对硬脑膜尾征及其对复发的临床影响进行进一步系统研究的必要性。临床试验编号：不适用。
