Xiang Yuqian, Yan Xiaohui, Shi Chenglong, Zhu Zhipeng, Zhang Min, Li Jiulong, Li Yanshuo, Wu Dapeng
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, State Key Laboratory Base of Novel Functional Materials and Preparation Science, School of Materials Science & Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, China.
Ningbo Zhongjin Petrochemical Co., Ltd., Ningbo, China.
J Chromatogr A. 2025 Aug 30;1757:466154. doi: 10.1016/j.chroma.2025.466154. Epub 2025 Jun 17.
In order to facilitate the application of nanomaterials in sample preparation, a scratching membrane method was proposed to prepare nanomaterial/polymer composite porous membranes, in which the type of nanomaterial and its loading amount could be tuned easily. The membranes were then ground and packed into cartridges for solid phase extraction (SPE) applications. In this work, multi-walled carbon nanotubes (MWCNT), nano carbon powder (NC), mesoporous silica (SBA-15), zeolitic imidazolate framework-8 (ZIF-8), Cu, and ZnO nanoparticles were chosen to prepare the corresponding composite porous membranes with polyacrylonitrile (PAN). The color and surface morphology of composite membranes were changed with the type and amount of incorporated nanoparticles. Large specific surface areas of 74.6-88.2 m g, along with abundant mesopores of ∼30 nm, enable rapid mass transfer for efficient extraction and elution. Among them, the 0.5 % MWCNT-5 % PAN membrane was chosen and used to extract aflatoxins (AFs) from water and peanut samples. Coupled with ultra-high performance liquid chromatography-fluorescence detection (UHPLC-FLD), some important SPE parameters were optimized, including sample solvents, sample pH, elution solvents and volume. Under optimal conditions, the method achieved a linear range of 0.05-10.0 μg l, recoveries of 86.91-104.57 %, LODs of 0.0016-0.0095 μg l in water samples, and a linear range of 2.5-50.0 μg l, recoveries of 86.5-111.1 %, LODs of 0.029-0.56 μg l in peanut samples. These results highlighted that nanomaterial/polymer composites could be prepared in a simple and cost-effective way, and employed as high-efficient SPE adsorbents.
为了便于纳米材料在样品制备中的应用，提出了一种刮膜法来制备纳米材料/聚合物复合多孔膜，其中纳米材料的类型及其负载量可以很容易地调节。然后将这些膜研磨并装入柱管用于固相萃取（SPE）应用。在这项工作中，选择了多壁碳纳米管（MWCNT）、纳米碳粉（NC）、介孔二氧化硅（SBA - 15）、沸石咪唑酯骨架 - 8（ZIF - 8）、铜和氧化锌纳米颗粒，以与聚丙烯腈（PAN）制备相应的复合多孔膜。复合膜的颜色和表面形态随掺入纳米颗粒的类型和数量而变化。74.6 - 88.2 m²/g的大比表面积以及约30 nm的丰富中孔，能够实现快速传质，以进行高效萃取和洗脱。其中，选择0.5% MWCNT - 5% PAN膜用于从水和花生样品中萃取黄曲霉毒素（AFs）。结合超高效液相色谱 - 荧光检测（UHPLC - FLD），优化了一些重要的SPE参数，包括样品溶剂、样品pH值、洗脱溶剂和体积。在最佳条件下，该方法在水样中的线性范围为0.05 - 10.0 μg/L，回收率为86.91 - 104.57%，检测限为0.0016 - 0.0095 μg/L；在花生样品中的线性范围为2.5 - 50.0 μg/L，回收率为范围为86.5 - 111.1%，检测限为0.029 - 0.56 μg/L。这些结果表明，纳米材料/聚合物复合材料可以通过简单且经济高效的方式制备，并用作高效的SPE吸附剂。
