• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

德国住院神经外科手术死亡率:对2023年住院数据的综合分析

Inpatient neurosurgical mortality in germany: a comprehensive analysis of 2023 in-hospital data.

作者信息

Kamp Marcel A, Jungk Christine, Schneider Matthias, Fehler Georgia, Santacroce Antonio, Dinc N, Ebner Florian H, von Sass Christiane

机构信息

Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Neuruppin, Germany.

Department of Palliative and Neuropalliative Care, Immanuel Clinic Rüdersdorf, University Hospital of the Brandenburg Medical School Theodor Fontane, Rüdersdorf bei Berlin, Seebad 82/83, 15562, Rüdersdorf near Berlin, Germany.

出版信息

Neurosurg Rev. 2025 Jun 23;48(1):525. doi: 10.1007/s10143-025-03664-1.

DOI:10.1007/s10143-025-03664-1
PMID:40545502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12183133/
Abstract

BACKGROUND

Neurosurgical conditions and procedures are associated with varying in-hospital mortality rates, which represent one of several quality indicators. This study aims to determine and report in-hospital mortality rates across German neurosurgical departments in 2023.

METHODS

A cross-sectional analysis of all neurosurgical cases treated in Germany in 2023 was conducted using nationwide hospital billing data reported under § 21 of the Hospital Remuneration Act. In-hospital mortality was defined as death during hospitalization (discharge status: deceased).

RESULTS

Neurosurgical departments treated 222,158 inpatient cases, with 49% female and 48% aged ≥ 65 years. The overall mortality rate was 3.8% (8,338 cases), with significantly lower rates in females (3.3% vs. 4.2%, p < 0.0001). The most common fatal diagnoses included traumatic subdural hematomas (1,278 cases), subcortical intracerebral hemorrhages (611 cases) and traumatic subarachnoid hemorrhages (504 cases). Mortality rates varied by diagnosis: malignant brain tumors (4%), cerebral metastases (6%), benign meningeal tumors (1.3%), non-traumatic subarachnoid hemorrhages (7%), intracerebral hemorrhages (29%), and traumatic subdural hematomas (12%). Mortality for selected procedures was 3% for primary brain tumor resections, 9% for vascular reconstructions, 1% for spinal fusions, 2% for dynamic stabilizations, and 4% for vertebral body replacements.

CONCLUSIONS

This study analyzes and reports neurosurgical in-hospital mortality rates in Germany, providing a national benchmark that may inform clinicians, policymakers, and patients. While the use of administrative billing data imposes inherent limitations - particularly regarding clinical detail and causality - the findings may offer a foundation for future research. Subsequent studies should aim to explore disease- and procedure-specific mortality more granularly and may identify underlying risk factors.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

神经外科疾病及手术的院内死亡率各不相同,这是多项质量指标之一。本研究旨在确定并报告2023年德国各神经外科科室的院内死亡率。

方法

利用《医院薪酬法》第21条规定上报的全国医院计费数据,对2023年德国治疗的所有神经外科病例进行横断面分析。院内死亡定义为住院期间死亡(出院状态:已死亡)。

结果

神经外科科室共治疗了222,158例住院病例,其中49%为女性,48%年龄≥65岁。总体死亡率为3.8%(8338例),女性死亡率显著较低(3.3%对4.2%,p<0.0001)。最常见的致命诊断包括创伤性硬膜下血肿(1278例)、皮质下脑出血(611例)和创伤性蛛网膜下腔出血(504例)。死亡率因诊断而异:恶性脑肿瘤(4%)、脑转移瘤(6%)、良性脑膜瘤(1.3%)、非创伤性蛛网膜下腔出血(7%)、脑出血(29%)和创伤性硬膜下血肿(12%)。特定手术的死亡率为:原发性脑肿瘤切除术3%,血管重建术9%,脊柱融合术1%,动态稳定术2%,椎体置换术4%。

结论

本研究分析并报告了德国神经外科的院内死亡率,提供了一个全国性基准,可为临床医生、政策制定者和患者提供参考。虽然使用行政计费数据存在固有局限性——尤其是在临床细节和因果关系方面——但研究结果可为未来研究提供基础。后续研究应更细致地探讨疾病和手术特定的死亡率,并可能识别潜在风险因素。

临床试验编号

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6079/12183133/db3162d5086f/10143_2025_3664_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6079/12183133/899246d2814b/10143_2025_3664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6079/12183133/db3162d5086f/10143_2025_3664_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6079/12183133/899246d2814b/10143_2025_3664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6079/12183133/db3162d5086f/10143_2025_3664_Fig2_HTML.jpg

相似文献

1
Inpatient neurosurgical mortality in germany: a comprehensive analysis of 2023 in-hospital data.德国住院神经外科手术死亡率:对2023年住院数据的综合分析
Neurosurg Rev. 2025 Jun 23;48(1):525. doi: 10.1007/s10143-025-03664-1.
2
Home treatment for mental health problems: a systematic review.心理健康问题的居家治疗:一项系统综述
Health Technol Assess. 2001;5(15):1-139. doi: 10.3310/hta5150.
3
Systemic treatments for metastatic cutaneous melanoma.转移性皮肤黑色素瘤的全身治疗
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.
4
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.在基层医疗机构或医院门诊环境中,如果患者出现以下症状和体征,可判断其是否患有 COVID-19。
Cochrane Database Syst Rev. 2022 May 20;5(5):CD013665. doi: 10.1002/14651858.CD013665.pub3.
5
Surveillance for Violent Deaths - National Violent Death Reporting System, 50 States, the District of Columbia, and Puerto Rico, 2022.暴力死亡监测——2022年全国暴力死亡报告系统,50个州、哥伦比亚特区和波多黎各
MMWR Surveill Summ. 2025 Jun 12;74(5):1-42. doi: 10.15585/mmwr.ss7405a1.
6
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
7
The measurement and monitoring of surgical adverse events.手术不良事件的测量与监测
Health Technol Assess. 2001;5(22):1-194. doi: 10.3310/hta5220.
8
Antibiotics for exacerbations of asthma.用于哮喘加重期的抗生素
Cochrane Database Syst Rev. 2018 Jun 25;6(6):CD002741. doi: 10.1002/14651858.CD002741.pub2.
9
Creating and validating a neurosurgical intervention rule-out tool for patients with mild traumatic brain injury and isolated subdural hematoma: a 5-year, six-center retrospective cohort study.创建并验证用于轻度创伤性脑损伤和单纯性硬膜下血肿患者的神经外科干预排除工具:一项为期5年的六中心回顾性队列研究。
J Neurosurg. 2024 Oct 11;142(3):839-850. doi: 10.3171/2024.5.JNS232478. Print 2025 Mar 1.
10
Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.非 ICU 住院患者预防谵妄的非药物干预措施。
Cochrane Database Syst Rev. 2021 Jul 19;7(7):CD013307. doi: 10.1002/14651858.CD013307.pub2.

本文引用的文献

1
The use of patient-reported outcome measures to improve patient-related outcomes - a systematic review.使用患者报告结局测量来改善患者相关结局——系统评价。
Health Qual Life Outcomes. 2024 Nov 26;22(1):101. doi: 10.1186/s12955-024-02312-4.
2
Machine Learning Algorithms for Neurosurgical Preoperative Planning: A Scoping Review.用于神经外科术前规划的机器学习算法:一项范围综述
World Neurosurg. 2025 Feb;194:123465. doi: 10.1016/j.wneu.2024.11.048. Epub 2024 Dec 5.
3
Visual deterioration secondary to medial sphenoid wing meningioma: systematic assessment of patient-reported outcomes and factors contributing to recovery after surgical treatment.
蝶骨嵴内侧脑膜瘤继发视力减退:对患者报告结局及手术治疗后恢复相关因素的系统评估
J Neurosurg. 2024 Oct 11;142(3):722-730. doi: 10.3171/2024.5.JNS232349. Print 2025 Mar 1.
4
Perioperative quality indicators among neurosurgery patients: A retrospective cohort study of 1142 cases at a tertiary center.神经外科患者围手术期质量指标:一家三级中心的 1142 例回顾性队列研究。
PLoS One. 2024 Feb 6;19(2):e0297167. doi: 10.1371/journal.pone.0297167. eCollection 2024.
5
Patient-reported outcome measures in cerebrovascular neurosurgery.脑血管外科学中的患者报告结局测量。
J Neurosurg. 2023 Nov 24;140(5):1357-1368. doi: 10.3171/2023.9.JNS231067. Print 2024 May 1.
6
Review of the Most Cited Patient-Reported Outcome Measure (PROM) Studies Published in the Neurospine Surgical Literature.神经脊柱外科文献中发表的被引用次数最多的患者报告结局测量(PROM)研究综述。
Cureus. 2023 Aug 28;15(8):e44262. doi: 10.7759/cureus.44262. eCollection 2023 Aug.
7
Frequency of social burden and underage children in neuro-oncological patients.神经肿瘤患者的社会负担和未成年子女的频率。
J Cancer Res Clin Oncol. 2023 Nov;149(17):15911-15922. doi: 10.1007/s00432-023-05338-1. Epub 2023 Sep 7.
8
National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.日本蛛网膜下腔出血结局的全国性趋势和卒中中心能力的预后影响:回顾性队列研究。
BMJ Open. 2023 Apr 10;13(4):e068642. doi: 10.1136/bmjopen-2022-068642.
9
Adverse events in neurosurgery: a comprehensive single-center analysis of a prospectively compiled database.神经外科的不良事件:前瞻性编译数据库的全面单中心分析。
Acta Neurochir (Wien). 2023 Mar;165(3):585-593. doi: 10.1007/s00701-022-05462-w. Epub 2023 Jan 10.
10
Mortality as an indicator of quality of neurosurgical care in England: a retrospective cohort study.英格兰神经外科护理质量的死亡率指标:一项回顾性队列研究。
BMJ Open. 2022 Nov 4;12(11):e067409. doi: 10.1136/bmjopen-2022-067409.