Hoffmann Thomas J, Tsoh Janice Y, Meyer Oanh L, Tzuang Marian, Nam Bora, Fara-On Gabriel, Huang Daren, Kanaya Alka M, Gallagher-Thompson Dolores, Vuong Quyen, Shin Hye-Won, Tofaeono Va'atausili, Grill Joshua D, Park Van Ta
Department of Epidemiology and Biostatistics, Institute for Human Genetics, and Office of Research School of Nursing, University of California, San Francisco, California, USA.
Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.
Alzheimers Dement. 2025 Jun;21(6):e70372. doi: 10.1002/alz.70372.
Elucidating barriers and facilitators to research participation is especially important in Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations, who are significantly underrepresented in Alzheimer's disease and related dementias (ADRD) research.
We analyzed multilingual data from the 7-item Research Attitude Questionnaire (RAQ) among diverse AANHPI participants across a broad age range in the Collaborative Approach for AANHPI Research and Education (CARE) registry.
Upon enrollment, 10,063 CARE participants were invited to complete the RAQ; 72.3% (7281) did so. The RAQ survey showed that 75.0% had favorable attitudes toward research. In a stepwise model, characteristics associated with a more favorable attitude toward research included identifying as Vietnamese, older age, providing multiple contact methods, living in the Western U.S. region, and having better general health.
Attitudes toward research differ based on specific characteristics. Certain subpopulations may require more tailored and/or resource-intensive engagement to increase their research participation.
Understanding research participation barriers is crucial in those underrepresented. Seventy-five percent of Collaborative Approach for Asian Americans, Native Hawaiians and Pacific Islanders Research and Education (CARE) registry members had favorable research attitudes. The study identified characteristics associated with research attitudes. Subpopulations may require more tailored and/or resource-intensive engagement.
阐明参与研究的障碍和促进因素在亚裔美国人、夏威夷原住民和太平洋岛民（AANHPI）群体中尤为重要，这些群体在阿尔茨海默病及相关痴呆症（ADRD）研究中的代表性严重不足。
我们分析了来自AANHPI研究与教育合作方法（CARE）登记处中不同年龄范围的AANHPI参与者的7项研究态度问卷（RAQ）的多语言数据。
登记时，邀请了10,063名CARE参与者完成RAQ；72.3%（7281名）完成了问卷。RAQ调查显示，75.0%的人对研究持积极态度。在逐步模型中，与对研究更积极态度相关的特征包括自我认同为越南人、年龄较大、提供多种联系方式、居住在美国西部地区以及总体健康状况较好。
对研究的态度因具体特征而异。某些亚群体可能需要更有针对性和/或资源密集型的参与方式来提高他们的研究参与度。
了解研究参与障碍在代表性不足的人群中至关重要。75%的亚裔美国人、夏威夷原住民和太平洋岛民研究与教育合作方法（CARE）登记处成员对研究持积极态度。该研究确定了与研究态度相关的特征。亚群体可能需要更有针对性和/或资源密集型的参与方式。
